第1巻 2005年6月　第3号

■綜説

臨床に呼応した迅速細胞診
前田　昭太郎¹, 横山　宗伯², 内藤　善哉^2
1日本医科大学付属多摩永山病院病理部
²日本医科大学病理学第二

Rapid Cytological Diagnosis Correlated with Clinical Medicine
Shotaro Maeda¹, Munehiro Yokoyama² and Zennya Naito^2
1Department of Pathology, Tama-Nagayama Hospital, Nippon Medical School
²Department of Pathology, Nippon Medical School

In recent years, diagnostic imaging methods, such as computed tomography, magnetic resonance imaging, and ultrasonography, have improved greatly and are now used to examine most internal organs. Recently, cytological diagnosis has been actively performed with diagnostic imaging, and treatment can often be started without diagnosis by excisional biopsy. However, few institutions perform rapid cytological diagnosis, and the usefulness of this rapid cytological diagnosis is not widely known. In our hospital, rapid cytological diagnosis has been performed routinely for 20 years. We perform rapid cytological diagnosis at the outpatient clinic, during operation, and even at autopsy, and have confirmed it to be useful. The main purpose of rapid cytological diagnosis at the outpatient clinic is to relieve patients from anxiety as soon as possible by providing early diagnosis and treatment. Rapid cytological diagnosis is often done for superficial sites, such as the breasts, thyroid glands, salivary glands, and lymph nodes. Intraoperative rapid cytological diagnosis has been performed to increase diagnostic accuracy. It is useful for body fluids, necrotic tissues, and small tissue samples that are not suitable for frozen section. Furthermore, if an infectious disease, such as tuberculosis, is suspected, an impression cytology specimen fixed in an alcohol solution is useful for biosafety. A rapid diagnosis at autopsy is important to inform the bereaved family about the cause of death and to ensure an accurate death certificate. Moreover, it is significant to diagnose by impression cytology for biosafety. Furthermore, we discuss about the usefulness of a rapid immunostaining method which is actively performed in our department for a rapid cytological diagnosis.

日医大医会誌 2005; 1(3), 102-109

Key words
cytology, rapid diagnosis, outpatient clinic, intraoperative, autopsy, immunostaining

Correspondence to
Shotaro Maeda, Department of Pathology, Tama-Nagayama Hospital, Nippon Medical School, 1-7-1 Nagayama, Tama, Tokyo 206-8512, Japan
E-mail：s-maeda@nms.ac.jp

受付：2005年4月21日　受理：2005年5月19日