第1巻 2005年10月　第4号

■特集　アレルギー・膠原病に対する新たな展開

アトピー性皮膚炎治療の未来
義澤　雄介
日本医科大学皮膚科学

The prevalence of atopic dermatitis has continued to increase in modern, highly industrialized countries. One concept to explain the increase is the hygiene hypothesis, which suggests that the increase in allergic disease is caused by a decreased exposure to childhood infections. After the hygiene hypothesis was described, epidemiological studies have been performed to evaluate the hypothesis from a standpoint of Th1/Th2 balance, and antiallergic therapies using microbes have been described. In this paper, novel strategies for the treatment of atopic dermatitis are introduced, including systemic immunotherapy using dinitrochlorobenzene and early intervention therapy and immunotherapy based on the hygiene hypothesis.

日医大医会誌 2005; 1(4), 207-209

Correspondence to
義澤雄介　〒113―8603　東京都文京区千駄木1―1―5　日本医科大学皮膚科学
E-mail：yyusuky@nms.ac.jp