■基礎研究から学ぶ
3.遺伝子導入と発現シリーズ ウイルスベクターによる遺伝子導入と発現(4)
三宅 弘一, 島田 隆
日本医科大学生化学・分子生物学(分子遺伝学)
3. Gene Delivery and Expression Series Viral Vector Mediated Gene Delivery and Expression (4)
Koichi Miyake and Takashi Shimada
Department of Biochemistry and Molecular Biology, Nippon Medical School

Viral vectors are powerful tools for gene delivery and expression both in vitro and in vivo. Recently, many types of viral vectors have become commercially available and are easily used. It is important to choose appropriate viral vectors according to target cells and organs. In this technical note, we describe the characteristics of viral vectors and how to choose the appropriate viral vector to transduce target cells in vitro.
日医大医会誌 2012; 8(2), 150-156
Key words
retroviral vector, lentiviral vector, adenoviral vector, adeno-associated viral vector
Correspondence to
Koichi Miyake, Department of Biochemistry and Molecular Biology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
E-mail:kmiyake@nms.ac.jp
受付:2012年2月13日 受理:2012年3月12日 |