第10巻 2014年4月　第2号

■綜説

脳の障害に対する可塑性と代償
三品　雅洋
日本医科大学大学院医学研究科神経内科学分野

Neural Plasticity and Compensation for Human Brain Damage
Masahiro Mishina
Department of Neurological Science, Graduate School of Medicine, Nippon Medical School

We previously believed that brain disorders could not be treated. However, brain-imaging techniques have demonstrated functional localization and the recovery of damaged areas of the brain. Through the use of various radiopharmaceuticals, positron emission tomography (PET) allows in vivo imaging of regional cerebral functions, including cerebral blood flow, molecular metabolism, and receptor binding capacity. In addition, PET demonstrates neural plasticity and compensation for brain damage. This paper discusses the plasticity and compensation of the brain revealed by our PET studies.

日医大医会誌 2014; 10(2), 101-105

Key words
positron emission tomography, γ-aminobutyric acid, aphasia, sigma₁ receptor, adenosine A_2A receptor

Correspondence to
Masahiro Mishina, Department of Neurological Science, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan
E-mail：mishina@nms.ac.jp

受付：2014年1月6日　受理：2014年1月23日