第11巻 2015年2月　第1号

■綜説

多発性内分泌腫瘍症2（Multiple endocrine neoplasia type 2：MEN2）医療の進歩
五十嵐　健人
日本医科大学内分泌外科

Recent Progress in Multiple Endocrine Neoplasia Type 2
Takehito Igarashi
Department of Endocrine Surgery, Nippon Medical School

Multiple endocrine neoplasia type 2 (MEN2) is an autosomal, predominantly hereditary disease characterized by medullary thyroid carcinoma, pheochromocytoma, and primary hyperparathyroidism; it is classified into type 2A, type 2B, and familial medullary thyroid carcinoma (FMTC). The last decade has seen improvements in the treatment and management of MEN2 in Japan. The establishment of a Japanese MEN database and the publication of a MEN clinical guidebook have played an important role in promoting effective management of the disease in our country. Our knowledge of MEN2 has expanded greatly, and in this review, I summarize our understanding of the disease based on recent discoveries.

日医大医会誌 2015; 11(1), 6-11

Key words
MEN2, endocrine surgery

Correspondence to
Takehito Igarashi, Department of Endocrine Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku Tokyo 113-8623, Japan
E-mail：takehito@nms.ac.jp

受付：2014年12月9日　受理：2014年12月18日