第14巻 2018年2月　第1号

■症例報告

皮膚原発腺様嚢胞癌2例の治療経験
香西　達一¹, 石井　暢明¹, 秋元　正宇¹, 櫻井　透¹, 森田　孝², 荻田　あづさ³, 安齋　眞一^{3, 4}, 小川　令^5
1日本医科大学千葉北総病院形成外科
²日本医科大学千葉北総病院皮膚科
³日本医科大学武蔵小杉病院皮膚科
⁴日本医科大学武蔵小杉病院皮膚病理診断室
⁵日本医科大学付属病院形成外科・再建外科・美容外科

Treatment Experience of Two Cases of Primary Cutaneous Adenoid Cystic Carcinoma
Michikazu Kozai¹, Nobuaki Ishii¹, Masataka Akimoto¹, Toru Sakurai¹, Takashi Morita², Azusa Ogita³, Shinichi Ansai^{3, 4} and Rei Ogawa^5
1)Department of Plastic and Reconstructive Surgery, Nippon Medical School Chiba Hokusoh Hospital
²⁾Department of Dermatology, Nippon Medical School Chiba Hokusoh Hospital
³⁾Division of Dermatology, Nippon Medical School Musashi Kosugi Hospital
⁴⁾Division of Dermatopathology, Nippon Medical School Musashi Kosugi Hospital
⁵⁾Department of Plastic, Reconstructive and Regenerative Surgery, Nippon Medical School

Primary cutaneous adenoid cystic carcinomas (ACCs) are rare. We report two cases of the primary cutaneous ACC. We resected dorsal crimson nodule in case 1 and resected crimson nodule of the back of the left side of head in case 2. Histopathological evaluation showed that luminal structure was formed of lumen epithelial cells and myoepithelial cells. The structure gathered and formed a cribriform pattern. Additionally, neuronal invasion was noted. No other obvious primary lesions were detected during the systemic examination. According to these findings, we therefore diagnosed this tumor as a primary cutaneous adenoid cystic carcinoma. Resection with an approximately 30 mm margin in both cases was performed. Local recurrence and metastasis are not detected now. ACC often shows neuronal invasion and local recurrence. Therefore, extended resection and a long-term follow-up are needed. When a skin tumor is examined, ACC should always be taken into consideration.

日医大医会誌 2018; 14(1), 25-30

Key words
primary cutaneous adenoid cystic carcinoma, cribriform pattern, neuronal invasion, local recurrence

Correspondence to
Michikazu Kozai, Department of Plastic and Reconstructive Surgery, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inzai Chiba 270-1694, Japan
E-mail：m-kozai@nms.ac.jp

受付：2017年11月30日　受理：2017年12月8日