第18巻 2022年8月　第3号

■症例報告

反復する細菌性髄膜炎の管理に難渋したMondini奇形
小林　光一¹, 早川　潤¹, 佐野　透美¹, 楊井　瑛美¹, 竹下　輝¹, 橋本　康司¹, 田嶋　華子¹, 五十嵐　徹¹, 川上　康彦², 右田　真^1
1日本医科大学武蔵小杉病院周産期・小児医療センター小児科
²日本医科大学多摩永山病院小児科

A Case of Recurrent Bacterial Meningitis in a Girl with Mondini Deformity
Koichi Kobayashi¹, Jun Hayakawa¹, Tomi Sano¹, Emi Yanai¹, Hikaru Takeshita¹, Kouji Hashimoto¹, Hanako Tajima¹, Toru Igarashi¹, Yasuhiko Kawakami² and Makoto Migita^1
1)Department of Pediatrics, Medical Center for Maternal and Child Health, Nippon Medical School Musashi Kosugi Hospital
²⁾Department of Pediatrics, Nippon Medical School Tama Nagayama Hospital

Delayed diagnosis of bacterial meningitis has a significant impact on prognosis and should not be overlooked. Cases of recurrent bacterial meningitis in infancy may be associated with underlying diseases such as immunodeficiencies and congenital deformities, including those of the inner ear. Streptococcus pneumoniae is a highly invasive causative agent, but the number of patients with meningitis has decreased dramatically in recent years due to the widespread use of the 13-valent pneumococcal conjugate vaccine. However, cases of vaccinated patients having invasive pneumococcal infection have been reported due to serotypes changing. We report a case of recurrent bacterial meningitis in an infant. The second occurrence was associated with Mondini deformity, for which surgical treatment was planned. The third was observed while the patient was awaiting surgery, and the fourth postoperatively. This study presents the clinical course of the Mondini deformity in this patient, which was difficult to manage due to the recurrent bacterial meningitis, and draws on epidemiological data concerning invasive pneumococcal infections occurring between April 2013 and March 2021 in Kawasaki City, Kanagawa Prefecture, Japan.

日医大医会誌 2022; 18(3), 299-303

Key words
Mondini deformity, recurrent bacterial meningitis, invasive pneumococcal disease, 24F

Correspondence to
Koichi Kobayashi, MD, Department of Pediatrics, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
E-mail：s11-037kk@nms.ac.jp

受付：2022年4月28日　受理：2022年5月17日