Journal of Nippon Medical School: Vol.67 No.4 page.271

Journal of Nippon Medical School

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ArticleTitle Multiple Fish Vertebra Deformity in Child with Systemic Lupus Erythematosus -A Case Report-

AuthorList Daiya Ozaki¹, Yasumasa Shirai¹, Yoshihito Nakayama¹, Kiyoshi Yoshihara¹ and Takehisa Huzita²

Affiliation ¹Department of Orthopedic Surgery, Nippon Medical School ²Department of Pediatrics, Nippon Medical School 2nd Hospital

Language EN

Volume 67

Issue 4

Year 2000

Page 271-274

Received January 7, 2000

Accepted March 27, 2000

Keywords systemic lupus erythematosus, fish vertebra deformity, child

Abstract We report an 11-year-old female patient with multiple fish vertebra deformity, which occurred in the course of treatment with corticosteroids for systemic lupus erythematosus (SLE). She was treated for SLE with predonisolone (30 mg per day) from April 2, 1996, and presented at our outpatient clinic for an osteoporosis check-up on April 27. She was 132 cm tall with-1.7 standard deviation of the average height, and X-ray examination revealed no evidence of osteoporosis in the spine. Bone mineral density (BMD) was 74.7% of the average BMD. Subsequently, she grew to 136 cm in September. However she began to have low back pain (LBP) from November, and received alfacalcidol. LBP deteriorated after pulse therapy with methylpredonisolone. In June 1997, X-ray examination revealed multiple fish vertebra deformity with 58.3% of the average BMD. Moreover her height had decreased to 131cm. She underwent combination therapy with elcatonin and alfacalcidol. In September 1999, she had no LBP nor progression of fish vertebra deformity. However she had no growth in height. Corticoseroids and SLE have multiple effects on bone metabolism, making the treatment of porosis complicated and difficult.

Correspondence to Daiya Ozaki, M. D. , Department of Orthopedic Surgery, Nippon Medical School 2nd Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan
daiya@nms.ac.jp

ArticleTitle	Multiple Fish Vertebra Deformity in Child with Systemic Lupus Erythematosus -A Case Report-
AuthorList	Daiya Ozaki¹, Yasumasa Shirai¹, Yoshihito Nakayama¹, Kiyoshi Yoshihara¹ and Takehisa Huzita²
Affiliation	¹Department of Orthopedic Surgery, Nippon Medical School ²Department of Pediatrics, Nippon Medical School 2nd Hospital
Language	EN
Volume	67
Issue	4
Year	2000
Page	271-274
Received	January 7, 2000
Accepted	March 27, 2000
Keywords	systemic lupus erythematosus, fish vertebra deformity, child
Abstract	We report an 11-year-old female patient with multiple fish vertebra deformity, which occurred in the course of treatment with corticosteroids for systemic lupus erythematosus (SLE). She was treated for SLE with predonisolone (30 mg per day) from April 2, 1996, and presented at our outpatient clinic for an osteoporosis check-up on April 27. She was 132 cm tall with-1.7 standard deviation of the average height, and X-ray examination revealed no evidence of osteoporosis in the spine. Bone mineral density (BMD) was 74.7% of the average BMD. Subsequently, she grew to 136 cm in September. However she began to have low back pain (LBP) from November, and received alfacalcidol. LBP deteriorated after pulse therapy with methylpredonisolone. In June 1997, X-ray examination revealed multiple fish vertebra deformity with 58.3% of the average BMD. Moreover her height had decreased to 131cm. She underwent combination therapy with elcatonin and alfacalcidol. In September 1999, she had no LBP nor progression of fish vertebra deformity. However she had no growth in height. Corticoseroids and SLE have multiple effects on bone metabolism, making the treatment of porosis complicated and difficult.
Correspondence to	Daiya Ozaki, M. D. , Department of Orthopedic Surgery, Nippon Medical School 2nd Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan daiya@nms.ac.jp