Journal of Nippon Medical School: Vol.67 No.6 page.455

Journal of Nippon Medical School

Select Language
in Japanese < > in English

Full Text of this Article

in English PDF (142k)

ArticleTitle Surgical Treatment of Coarctation Complex in Neonates and Infants

AuthorList Hitoshi Yamauchi¹, Masahiro Fujii¹, Hideyuki Iwaki¹, Yosuke Ishii¹, Yoshiaki Saji¹, Yuji Maruyama¹, Hiromasa Yamashita¹, Yoko Uchikoba², Ryuji Fukazawa², Takashi Okubo², Shunichi Ogawa² and Shigeo Tanaka¹

Affiliation ¹Department of Surgery II·Division of Cardiovascular Surgery and ²Department of Pediatrics, Nippon Medical School

Language EN

Volume 67

Issue 6

Year 2000

Page 455-458

Received June 30, 2000

Accepted August 7, 2000

Keywords coarctation complex, two-stage repair, subclavian flap aortoplasty

Abstract Background: There remains controversy regarding the appropriate surgical treatment of coarctation of the aorta associated with intracardiac anomalies in neonates and infants. Furthermore, the relative benefits of one versus two-stage repair, and subclavian flap aortoplasty versus end-to-end anastomosis for some of these lesions, remain controversial. The purpose of this paper is to review our experience with two-stage repair using subclavian flap aortoplasty and to seek an appropriate procedure.
Methods and Result: From June 1996 to November 1999, thirteen patients underwent subclavian flap aortoplasty in our department. The age range was 16 to 101 days (mean 52 days), and the body weight range was 1.9 to 4.5 kg (mean 3.0 kg). Anatomic diagnosis was coarctation with ventricular septal defect (six patients), double outlet right ventricle (two patients), atrioventricular canal defect (one patient), tricuspid atresia (two patients), mitral atresia (one patient), and single atrium and subaortic stenosis (one patient). There was one hospital death in our series due to the progression of pulmonary hypertension 3 months after the operation. The mean follow up for remaining twelve patients was 28 months (range 7~48 months). There was one reoperation for recurrent coarctation. Three patients underwent pulmonary artery plasty in a second operation because of right pulmonary artery stenosis. We performed the definitive operation for six patients with coarctation with ventricular septal defect and two patients with double outlet right ventricle, and we performed a bidirectional cavopulmonary shunt for four univentricular hearts who are candidates for the Fontan operation. Two patients required Damus-Kaye-Stansel procedure to release restrictive bulboventricular foramen. Three patients underwent a modified Fontan operation after these palliations. In our series, the intraoperative mortality rate for subclavian flap aortoplasty was 0% and the post operative mortality rate was 7.7% (1/13). Ten patients underwent the final operation successfully, and further two patients are considered good candidates for the final operation. The overall mortality was 7.7% (1/13).
Conclusion: Two-stage repair appears to offer a good prognosis for neonates and infants with a coarctation complex. Subclavian flap aortoplasty showed the lowest rate of restenosis. However, late mortality may be associated with the progression of pulmonary vascular disease and the presence of associated severe cardiac anomalies. Although Fontan candidates need staged operations, if biventricular repair is feasible, one-stage repair would be a reasonable procedure considering the progression of the pulmonary vascular disease and the distortion of the pulmonary artery due to pulmonary artery banding. It would appear to improve the quality of life of those children if a one-stage operation can be performed with reasonable risk and good midterm outcome.

Correspondence to Hitoshi Yamauchi, MD, Department of Surgery II·Division of Cardiovascular Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan
yamauchi_hitoshi/surg2@nms.ac.jp

ArticleTitle	Surgical Treatment of Coarctation Complex in Neonates and Infants
AuthorList	Hitoshi Yamauchi¹, Masahiro Fujii¹, Hideyuki Iwaki¹, Yosuke Ishii¹, Yoshiaki Saji¹, Yuji Maruyama¹, Hiromasa Yamashita¹, Yoko Uchikoba², Ryuji Fukazawa², Takashi Okubo², Shunichi Ogawa² and Shigeo Tanaka¹
Affiliation	¹Department of Surgery II·Division of Cardiovascular Surgery and ²Department of Pediatrics, Nippon Medical School
Language	EN
Volume	67
Issue	6
Year	2000
Page	455-458
Received	June 30, 2000
Accepted	August 7, 2000
Keywords	coarctation complex, two-stage repair, subclavian flap aortoplasty
Abstract	Background: There remains controversy regarding the appropriate surgical treatment of coarctation of the aorta associated with intracardiac anomalies in neonates and infants. Furthermore, the relative benefits of one versus two-stage repair, and subclavian flap aortoplasty versus end-to-end anastomosis for some of these lesions, remain controversial. The purpose of this paper is to review our experience with two-stage repair using subclavian flap aortoplasty and to seek an appropriate procedure. Methods and Result: From June 1996 to November 1999, thirteen patients underwent subclavian flap aortoplasty in our department. The age range was 16 to 101 days (mean 52 days), and the body weight range was 1.9 to 4.5 kg (mean 3.0 kg). Anatomic diagnosis was coarctation with ventricular septal defect (six patients), double outlet right ventricle (two patients), atrioventricular canal defect (one patient), tricuspid atresia (two patients), mitral atresia (one patient), and single atrium and subaortic stenosis (one patient). There was one hospital death in our series due to the progression of pulmonary hypertension 3 months after the operation. The mean follow up for remaining twelve patients was 28 months (range 7~48 months). There was one reoperation for recurrent coarctation. Three patients underwent pulmonary artery plasty in a second operation because of right pulmonary artery stenosis. We performed the definitive operation for six patients with coarctation with ventricular septal defect and two patients with double outlet right ventricle, and we performed a bidirectional cavopulmonary shunt for four univentricular hearts who are candidates for the Fontan operation. Two patients required Damus-Kaye-Stansel procedure to release restrictive bulboventricular foramen. Three patients underwent a modified Fontan operation after these palliations. In our series, the intraoperative mortality rate for subclavian flap aortoplasty was 0% and the post operative mortality rate was 7.7% (1/13). Ten patients underwent the final operation successfully, and further two patients are considered good candidates for the final operation. The overall mortality was 7.7% (1/13). Conclusion: Two-stage repair appears to offer a good prognosis for neonates and infants with a coarctation complex. Subclavian flap aortoplasty showed the lowest rate of restenosis. However, late mortality may be associated with the progression of pulmonary vascular disease and the presence of associated severe cardiac anomalies. Although Fontan candidates need staged operations, if biventricular repair is feasible, one-stage repair would be a reasonable procedure considering the progression of the pulmonary vascular disease and the distortion of the pulmonary artery due to pulmonary artery banding. It would appear to improve the quality of life of those children if a one-stage operation can be performed with reasonable risk and good midterm outcome.
Correspondence to	Hitoshi Yamauchi, MD, Department of Surgery II·Division of Cardiovascular Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan yamauchi_hitoshi/surg2@nms.ac.jp