Journal of Nippon Medical School: Vol.68 No.5 page.393

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ArticleTitle Wide-spread Distribution of Sentinel Lymph nodes in Esophageal Cancer

AuthorList Tsutomu Nomura¹, Masahiko Onda¹, Masao Miyashita¹, Hiroshi Makino¹, Hiroshi Maruyama¹, Shigenao Nagasawa¹, Ryouhei Futami¹, Kiyohiko Yamashita¹, Kaiyo Takubo² and Koji Sasajima¹

Affiliation ¹Department of Surgery I, Nippon Medical School, ²Department of Clinical Pathology, Tokyo Metropolitan Institute of Gerontology, Tokyo

Language EN

Volume 68

Issue 5

Year 2001

Page 393-396

Received March 26, 2001

Accepted April 24, 2001

Keywords sentinel lymph node, esophageal cancer, esophagectomy, lymphadenectomy, skip metastasis

Abstract Sentinel lymph nodes are the first draining nodes that contain tumor cells. Identification of sentinel nodes may help to determine the suitable extent of lymphadenectoy. To assess the location of sentinel lymph nodes, a series of 41 patients with single and two metastatic lymph nodes who underwent esophagectomy and 3-field lymphadenectomy between 1991 and 1999 were investigated retrospectively. Only 29 (47.5%) of 61 metastatic nodes showed correspondence between the tumor site and the regional metastatic lymph nodes by routine histologic examination. In the patients with tumors in the upper and middle thoracic esophagus, metastatic lymph nodes were distributed in the cervix, mediastinum and abdomen. Although sentinel nodes were limited to the regional and adjusting compartments in 82%, nodes were found beyond the adjusting compartments in 18%. The sentinel nodes were broadly distributed depending on the location of the tumor in esophageal cancer.

Correspondence to Tsutomu Nomura, MD, Department of Surgery I, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
nomura-t/surg1@nms.ac.jp

ArticleTitle	Wide-spread Distribution of Sentinel Lymph nodes in Esophageal Cancer
AuthorList	Tsutomu Nomura¹, Masahiko Onda¹, Masao Miyashita¹, Hiroshi Makino¹, Hiroshi Maruyama¹, Shigenao Nagasawa¹, Ryouhei Futami¹, Kiyohiko Yamashita¹, Kaiyo Takubo² and Koji Sasajima¹
Affiliation	¹Department of Surgery I, Nippon Medical School, ²Department of Clinical Pathology, Tokyo Metropolitan Institute of Gerontology, Tokyo
Language	EN
Volume	68
Issue	5
Year	2001
Page	393-396
Received	March 26, 2001
Accepted	April 24, 2001
Keywords	sentinel lymph node, esophageal cancer, esophagectomy, lymphadenectomy, skip metastasis
Abstract	Sentinel lymph nodes are the first draining nodes that contain tumor cells. Identification of sentinel nodes may help to determine the suitable extent of lymphadenectoy. To assess the location of sentinel lymph nodes, a series of 41 patients with single and two metastatic lymph nodes who underwent esophagectomy and 3-field lymphadenectomy between 1991 and 1999 were investigated retrospectively. Only 29 (47.5%) of 61 metastatic nodes showed correspondence between the tumor site and the regional metastatic lymph nodes by routine histologic examination. In the patients with tumors in the upper and middle thoracic esophagus, metastatic lymph nodes were distributed in the cervix, mediastinum and abdomen. Although sentinel nodes were limited to the regional and adjusting compartments in 82%, nodes were found beyond the adjusting compartments in 18%. The sentinel nodes were broadly distributed depending on the location of the tumor in esophageal cancer.
Correspondence to	Tsutomu Nomura, MD, Department of Surgery I, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan nomura-t/surg1@nms.ac.jp