Journal of Nippon Medical School: Vol.68 No.5 page.435

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ArticleTitle Gastrointestinal Stromal Tumor of the Stomach Diagnosed Preoperatively

AuthorList Kimiyoshi Yokoi¹, Kiyohiko Yamashita¹, Noritake Tanaka¹, Shouji Kyouno¹, Noriyuki Ishikawa¹, Tomoko Seya¹, Yoshiharu Ohaki², Naoyuki Yamashita³ and Masahiko Onda³

Affiliation Department of ¹Surgery and ²Pathology, Chiba Hokusoh Hospital, Nippon Medical School, ³First Department of Surgery, Nippon Medical School

Language EN

Volume 68

Issue 5

Year 2001

Page 435-441

Received April 13, 2001

Accepted May 8, 2001

Keywords GIST, submucosal tumor, preoperative diagnosis, surgical procedure, stomach

Abstract A case of gastrointestinal stromal tumor (GIST) of the stomach is reported. GIST has been applied to gastrointestinal submucosal tumors mainly composed of spindle shaped cells that represent neither typical features of myogenic nor neurogenic tumors, and immunohistochemical studies are necessary for the diagnosis of GIST.
The patient was a 39-year-old man and was successfully diagnosed to be GIST (uncommitted type) preoperatively by immunohistochemical studies of biopsy specimens from an ulcerative submucosal tumor with bridging folds in the fundus, approximately 3.0 cm in size. Local excision of the stomach was performed. This is the 3rd case of GIST with a preoperative diagnosis to appear in the literature in Japan.
For gastroenterological surgeons, it is critical to select the most suitable surgical procedure. In the present, because the number of papers reporting GIST of the stomach is small, it is impossible to review GIST clinicopathologically. We reviewed the surgical procedure for gastric leiomyosarcomas, because of including many cases with GIST in them. Therefore, we performed 54 cases of gastric GIST in the literature, compared with 92 cases of gastric leiomyosarcoma. As a result, it was thought that local excision for gastric GIST should be preferred.

Correspondence to Kimiyoshi Yokoi, MD, Department of Surgery, Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagaya, Inba-mura, Inba-gun, Chiba 270-1694, Japan

ArticleTitle	Gastrointestinal Stromal Tumor of the Stomach Diagnosed Preoperatively
AuthorList	Kimiyoshi Yokoi¹, Kiyohiko Yamashita¹, Noritake Tanaka¹, Shouji Kyouno¹, Noriyuki Ishikawa¹, Tomoko Seya¹, Yoshiharu Ohaki², Naoyuki Yamashita³ and Masahiko Onda³
Affiliation	Department of ¹Surgery and ²Pathology, Chiba Hokusoh Hospital, Nippon Medical School, ³First Department of Surgery, Nippon Medical School
Language	EN
Volume	68
Issue	5
Year	2001
Page	435-441
Received	April 13, 2001
Accepted	May 8, 2001
Keywords	GIST, submucosal tumor, preoperative diagnosis, surgical procedure, stomach
Abstract	A case of gastrointestinal stromal tumor (GIST) of the stomach is reported. GIST has been applied to gastrointestinal submucosal tumors mainly composed of spindle shaped cells that represent neither typical features of myogenic nor neurogenic tumors, and immunohistochemical studies are necessary for the diagnosis of GIST. The patient was a 39-year-old man and was successfully diagnosed to be GIST (uncommitted type) preoperatively by immunohistochemical studies of biopsy specimens from an ulcerative submucosal tumor with bridging folds in the fundus, approximately 3.0 cm in size. Local excision of the stomach was performed. This is the 3rd case of GIST with a preoperative diagnosis to appear in the literature in Japan. For gastroenterological surgeons, it is critical to select the most suitable surgical procedure. In the present, because the number of papers reporting GIST of the stomach is small, it is impossible to review GIST clinicopathologically. We reviewed the surgical procedure for gastric leiomyosarcomas, because of including many cases with GIST in them. Therefore, we performed 54 cases of gastric GIST in the literature, compared with 92 cases of gastric leiomyosarcoma. As a result, it was thought that local excision for gastric GIST should be preferred.
Correspondence to	Kimiyoshi Yokoi, MD, Department of Surgery, Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagaya, Inba-mura, Inba-gun, Chiba 270-1694, Japan