Journal of Nippon Medical School: Vol.69 No.1 page.024

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ArticleTitle Breast-Conserving Therapy in the Management of EarlyStage Breast Cancer: Our Experience in 103 Cases

AuthorList Tsuguhiro Miyashita¹, Atsushi Tateno¹, Tatsuo Kumazaki¹, Kiyonori Furukawa², Kaori Minobe² and Kazuo Shimizu³

Affiliation ¹Department of Radiology, Nippon Medical School, ²First and ³Second Departments of Surgery, Nippon Medical School

Language EN

Volume 69

Issue 1

Year 2002

Page 24-30

Received May 22, 2001

Accepted July25, 2002

Keywords breast cancer, breastconserving therapy, surgery, radiation therapy

Abstract Purpose: The aim of this study is to determine whether our results in breastconserving therapy of 103 patients with earlystage breast cancer are comparable to those of other facilities or not.
Materials and methods: From January 1990 to October 1999, 103 patients with earlystage breast cancer were treated by breastconserving surgery and whole breast irradiation. All patients were of Stages I or II, and the greatest dimensions of primary tumor were less than 3 cm. The median followup time was 47 months from the completion of postoperative radiotherapy. Local, regional and distant failure rates, and survival rate were presumed using the KaplanMeyer method.
Results: One patient suffered from local recurrence 30 months later. She was followed by simple mastectomy and kept from further recurrence. No regional relapse occurred. Distant metastases were seen in three patients:two patients in bones, and one patient in a bone and the liver after 19, 35, and 32 months, respectively. One patient died from disseminated cancer in 41 months. Only one patient died due to intercurrent disease. Both 5year and 10year diseasefree survival rates were 94.2%, and both 5year and 10year causespecific survival rates were 98.3%.
Conclusion: Our results were comparable to previously reported data. In this stage although the followup time was too short to define the longterm outcome, it suggested that breast conserving therapy was acceptable and effective in the management of earlystage breast cancer.

Correspondence to Tsuguhiro Miyashita, MD, Department of Radiology, Nippon Medical School, 1-1-5 Sendagi, Bunkyoku, Tokyo 113-8603, Japan
miyasita@nms.ac.jp

ArticleTitle	Breast-Conserving Therapy in the Management of EarlyStage Breast Cancer: Our Experience in 103 Cases
AuthorList	Tsuguhiro Miyashita¹, Atsushi Tateno¹, Tatsuo Kumazaki¹, Kiyonori Furukawa², Kaori Minobe² and Kazuo Shimizu³
Affiliation	¹Department of Radiology, Nippon Medical School, ²First and ³Second Departments of Surgery, Nippon Medical School
Language	EN
Volume	69
Issue	1
Year	2002
Page	24-30
Received	May 22, 2001
Accepted	July25, 2002
Keywords	breast cancer, breastconserving therapy, surgery, radiation therapy
Abstract	Purpose: The aim of this study is to determine whether our results in breastconserving therapy of 103 patients with earlystage breast cancer are comparable to those of other facilities or not. Materials and methods: From January 1990 to October 1999, 103 patients with earlystage breast cancer were treated by breastconserving surgery and whole breast irradiation. All patients were of Stages I or II, and the greatest dimensions of primary tumor were less than 3 cm. The median followup time was 47 months from the completion of postoperative radiotherapy. Local, regional and distant failure rates, and survival rate were presumed using the KaplanMeyer method. Results: One patient suffered from local recurrence 30 months later. She was followed by simple mastectomy and kept from further recurrence. No regional relapse occurred. Distant metastases were seen in three patients:two patients in bones, and one patient in a bone and the liver after 19, 35, and 32 months, respectively. One patient died from disseminated cancer in 41 months. Only one patient died due to intercurrent disease. Both 5year and 10year diseasefree survival rates were 94.2%, and both 5year and 10year causespecific survival rates were 98.3%. Conclusion: Our results were comparable to previously reported data. In this stage although the followup time was too short to define the longterm outcome, it suggested that breast conserving therapy was acceptable and effective in the management of earlystage breast cancer.
Correspondence to	Tsuguhiro Miyashita, MD, Department of Radiology, Nippon Medical School, 1-1-5 Sendagi, Bunkyoku, Tokyo 113-8603, Japan miyasita@nms.ac.jp