Journal of Nippon Medical School: Vol.69 No.4 page.328

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ArticleTitle Assessment of Endometrial Perfusion with Doppler Ultrasound in Spontaneous and Stimulated Menstrual Cycles

AuthorList Akihito Nakai, Akishige Yokota, Tatsuo Koshino and Tsutomu Araki

Affiliation Department of Obstetrics and Gynecology, Nippon Medical School

Language EN

Volume 69

Issue 4

Year 2002

Page 328-332

Received September 26, 2001

Accepted January 21, 2002

Keywords ultrasonography, infertility, endometrial perfusion, clomiphene citrate

Abstract Objective: Endometrial perfusions were measured by Doppler ultrasound to evaluate the influence of spontaneous menstrual cycles and to study the effect of clomiphene citrate.
Methods: Flow waveforms in right and left uterine arteries were obtained by using transvaginal color Doppler ultrasonography in infertile women with 60 spontaneous menstrual cycles and 37 clomiphene citrate stimulated cycles from the follicular to the luteal phase.
Results: In the spontaneous menstrual cycles, the uterine arterial blood flow increased significantly from the follicular phase to the day of ovulation and then increased markedly to about 200∼230% of the follicular phase after the 6th day of ovulation. In the clomiphene citrate stimulated cycles, the uterine arterial blood flow did not change during the periovulatory period and then increased significantly to about 180∼220% of the follicular phase after the 6th day of ovulation.
Conclusions: In the present study, the clomiphene citrate stimulated cycles showed lower endometrial perfusion during the periovulatory period compared with those in the spontaneous menstrual cycles. The results suggest that the assessment of endometrial perfusion with Doppler ultrasound can be used to reveal unexplained infertility problems in induced ovarian cycles.

Correspondence to Akihito Nakai, MD, Department of Obstetrics and Gynecology, Tama Nagayama Hospital, Nippon Medical School, 1-7-1 Nagayama, Tama-shi, Tokyo 206-8512, Japan
nakai-3@nms.ac.jp

ArticleTitle	Assessment of Endometrial Perfusion with Doppler Ultrasound in Spontaneous and Stimulated Menstrual Cycles
AuthorList	Akihito Nakai, Akishige Yokota, Tatsuo Koshino and Tsutomu Araki
Affiliation	Department of Obstetrics and Gynecology, Nippon Medical School
Language	EN
Volume	69
Issue	4
Year	2002
Page	328-332
Received	September 26, 2001
Accepted	January 21, 2002
Keywords	ultrasonography, infertility, endometrial perfusion, clomiphene citrate
Abstract	Objective: Endometrial perfusions were measured by Doppler ultrasound to evaluate the influence of spontaneous menstrual cycles and to study the effect of clomiphene citrate. Methods: Flow waveforms in right and left uterine arteries were obtained by using transvaginal color Doppler ultrasonography in infertile women with 60 spontaneous menstrual cycles and 37 clomiphene citrate stimulated cycles from the follicular to the luteal phase. Results: In the spontaneous menstrual cycles, the uterine arterial blood flow increased significantly from the follicular phase to the day of ovulation and then increased markedly to about 200∼230% of the follicular phase after the 6th day of ovulation. In the clomiphene citrate stimulated cycles, the uterine arterial blood flow did not change during the periovulatory period and then increased significantly to about 180∼220% of the follicular phase after the 6th day of ovulation. Conclusions: In the present study, the clomiphene citrate stimulated cycles showed lower endometrial perfusion during the periovulatory period compared with those in the spontaneous menstrual cycles. The results suggest that the assessment of endometrial perfusion with Doppler ultrasound can be used to reveal unexplained infertility problems in induced ovarian cycles.
Correspondence to	Akihito Nakai, MD, Department of Obstetrics and Gynecology, Tama Nagayama Hospital, Nippon Medical School, 1-7-1 Nagayama, Tama-shi, Tokyo 206-8512, Japan nakai-3@nms.ac.jp