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ArticleTitle | Relationship Between Grade of Fibrosis in Pancreatic Stump and Postoperative Pancreatic Exocrine Activity After Pancreaticoduodenectomy: With Special Reference to Insufficiency of Pancreaticointestinal Anastomosis |
AuthorList | Eiji Uchida1, Takashi Tajiri1, Yoshiharu Nakamura1, Takayuki Aimoto1 and Zenya Naito2 |
Affiliation | 1First Department of Surgery, Nippon Medical School, 2Department of Pathology, Nippon Medical School |
Language | EN |
Volume | 69 |
Issue | 6 |
Year | 2002 |
Page | 549-556 |
Received | May 27, 2002 |
Accepted | July 11, 2002 |
Keywords | pancreaticoduodenectomy, periampullary disease, complication, exocrine activity, fibrosis |
Abstract |
Background: Pancreaticoduodenectomy (PD) has become a standard operation for malignant and benign periampullary diseases. Although the operative mortality of PD has decreased to less than 4% in hospitals with many cases of PD, the leakage of pancreaticointestinal anastomosis (PIA) still carries a substantial risk of lethal outcome. The aim of this study was to evaluate the local factors that affect the incidence of PIA leakage by evaluation of exocrine function and fibrosis in the pancreatic remnant following PD. |
Correspondence to | Eiji Uchida, First Department of Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan uchida@nms.ac.jp |
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