Journal of Nippon Medical School: Vol.69 No.6 page.564

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ArticleTitle Histological Changes Elicited by Hair Removal Lasers

AuthorList Tokue Kato¹, Tokuya Omi^{1, 2}, Goro Asano³ and Seiji Kawana¹

Affiliation ¹Department of Dermatology, Nippon Medical School, ²Department of Dermatology, Queen's Square Medical Center, ³Department of Pathology, Nippon Medical School

Language JA

Volume 69

Issue 6

Year 2002

Page 564-570

Received July 27, 2001

Accepted June 5, 2002

Keywords laser hair removal, ruby laser, alexandrite laser, histology, laser fluence

Abstract
Several different laser systems are currently used to remove unwanted hairs. In this study, we studied follicular changes following hair removal with ruby or alexandrite lasers at different fluences.
Unwanted hairs were treated with a ruby laser (ICN, Photon Ics, UK) at 10, 14, 18 J/cm² or an alexandrite laser (Cynosure, USA) at 11, 14, 17 J/cm². A 3 mm punch biopsy was taken immediately after each laser exposure and one month later. Specimens were stained for histological observations. They were observed using immunohistochemistry to Factor VIII related antigen and PCNA, and also by the TUNEL method.
Immediately after the laser exposure, moderate follicular damage was observed following treatment with either laser. One month later, cystic formation of hair follicles and foreign body giant cells were observed in skin treated with either laser. The similar influence of each laser treatment resulted in similar histological changes.
In this study, the histological changes following treatment with a ruby or an alexandrite laser at the same fluence were considered to be similar.

Correspondence to Tokue Kato, Department of Dermatology, Nippon Medical school, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
tokue@nms.ac.jp

ArticleTitle	Histological Changes Elicited by Hair Removal Lasers
AuthorList	Tokue Kato¹, Tokuya Omi^{1, 2}, Goro Asano³ and Seiji Kawana¹
Affiliation	¹Department of Dermatology, Nippon Medical School, ²Department of Dermatology, Queen's Square Medical Center, ³Department of Pathology, Nippon Medical School
Language	JA
Volume	69
Issue	6
Year	2002
Page	564-570
Received	July 27, 2001
Accepted	June 5, 2002
Keywords	laser hair removal, ruby laser, alexandrite laser, histology, laser fluence
Abstract	Several different laser systems are currently used to remove unwanted hairs. In this study, we studied follicular changes following hair removal with ruby or alexandrite lasers at different fluences. Unwanted hairs were treated with a ruby laser (ICN, Photon Ics, UK) at 10, 14, 18 J/cm² or an alexandrite laser (Cynosure, USA) at 11, 14, 17 J/cm². A 3 mm punch biopsy was taken immediately after each laser exposure and one month later. Specimens were stained for histological observations. They were observed using immunohistochemistry to Factor VIII related antigen and PCNA, and also by the TUNEL method. Immediately after the laser exposure, moderate follicular damage was observed following treatment with either laser. One month later, cystic formation of hair follicles and foreign body giant cells were observed in skin treated with either laser. The similar influence of each laser treatment resulted in similar histological changes. In this study, the histological changes following treatment with a ruby or an alexandrite laser at the same fluence were considered to be similar.
Correspondence to	Tokue Kato, Department of Dermatology, Nippon Medical school, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan tokue@nms.ac.jp