Home > List of Issue > Table of Contents > Abstract

Journal of Nippon Medical School
Select Language
in Japanese < > in English

Full Text of this Article
in English PDF (108K)

ArticleTitle Serum Leptin Concentration in Young Adult Women with Ovulatory Dysfunction
AuthorList Hisayuki Kaseki1, Satomi Maruyama2, Kaisuke Ishihara1 and Tsutomu Araki1
Affiliation 1Department of Obstetrics and Gynecology, Nippon Medical School
2Graduate School of Nutrition, Showa Women's University
Language EN
Volume 70
Issue 3
Year 2003
Page 270-273
Received August 29, 2002
Accepted December 25, 2002
Keywords leptin, BMI, percent body fat, ovulation, ovulatory dysfunction
Abstract To investigate the functional role of leptin in human ovulation, we measured serum leptin, LH, FSH and estradiol in 16 young adult women suffering from ovulatory dysfunction with BMI ranging from17.5 to 24.5 (group A). The control subjects included 12 women with regular ovulation and matched age and BMI (group B). We found that serum leptin concentration in group A subjects was significantly lower than that in group B subjects (4.1±0.5 vs. 6.1±0.4 ng/ml, p<0.01). The percent body fat, estradiol, LH and FSH concentrations in groups A and B were not significantly different. These results indicate that anovulatory young adult women have lower leptin concentration than women with regular ovulation, thus suggesting a key role for leptin in regular ovulation or ovulatory dysfunction.
Correspondence to Hisayuki Kaseki MD, PhD, Department of Obstetrics and Gynecology, Nippon Medical School Second Hospital, 1-396 Kosugi-cho, Nakahara-Ku, Kawasaki, Kanagawa 211-8533, Japan

Copyright © The Medical Association of Nippon Medical School