Journal of Nippon Medical School: Vol.71 No.3 page.156

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ArticleTitle The Factors Affecting Glycemic Control in Japanese Adolescents with Type 2 Diabetes Mellitus

AuthorList Yukashi Ohki, Megumi Kishi, Hiromi Orimo and Takuya Ohkawa

Affiliation Department of Pediatrics, Nippon Medical School

Language EN

Volume 71

Issue 3

Year 2004

Page 156-159

Received September 1, 2003

Accepted October 8, 2003

Keywords type 2 diabetes, HbA_1C, drug therapy

Abstract
The factors affecting glycemic control were examined using HbA_1C as an index in a total of 22 patients with type 2 diabetes mellitus whose ages at onset were less than 18 years old. As a result, the presence or absence of the following cases were considered possible factors for significant exacerbation of glycemic control: diabetic microangiopathy; school phobia or nonworking situation; drug therapy; use of more than two kinds of oral hypoglycemic agents (OHAs) or insulin for the drug therapy cases.

No improvement in glycemic control could be achieved even by increasing the number of OHAs for co-administration or by insulin use unless dietary/exercise therapy, a basic therapeutic option, was adequately performed.

Correspondence to Yukashi Ohki, Department of Pediatrics, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
yukashi@nms.ac.jp

ArticleTitle	The Factors Affecting Glycemic Control in Japanese Adolescents with Type 2 Diabetes Mellitus
AuthorList	Yukashi Ohki, Megumi Kishi, Hiromi Orimo and Takuya Ohkawa
Affiliation	Department of Pediatrics, Nippon Medical School
Language	EN
Volume	71
Issue	3
Year	2004
Page	156-159
Received	September 1, 2003
Accepted	October 8, 2003
Keywords	type 2 diabetes, HbA_1C, drug therapy
Abstract	The factors affecting glycemic control were examined using HbA_1C as an index in a total of 22 patients with type 2 diabetes mellitus whose ages at onset were less than 18 years old. As a result, the presence or absence of the following cases were considered possible factors for significant exacerbation of glycemic control: diabetic microangiopathy; school phobia or nonworking situation; drug therapy; use of more than two kinds of oral hypoglycemic agents (OHAs) or insulin for the drug therapy cases. No improvement in glycemic control could be achieved even by increasing the number of OHAs for co-administration or by insulin use unless dietary/exercise therapy, a basic therapeutic option, was adequately performed.
Correspondence to	Yukashi Ohki, Department of Pediatrics, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan yukashi@nms.ac.jp