-Case Reports-

Urinary Tract Malformation and Infection with Hyperkalemia and Decreased Fractional Excretion of Potassium in an Infant

Takeshi Asano^1,2, Masanori Abe^1,2, Makiko Asai^1,2, Taiyoh Imai^1,2, Mitsuhiro Kamisago^1,2, Kentaroh Kuwabara^1,2, Mizue Nakajima^1,2, Mutsumi Murakami^1,2 and Osamu Fujino^1,2

¹Department of Pediatrics, Nippon Medical School Graduate School of Medicine
²Department of Pediatrics, Chiba-Hokusoh Hospital, Nippon Medical School

We describe an uncircumcised male infant treated for urinary tract infection who exhibited multiple hormonal and electrolyte abnormalities consistent with a diagnosis of transient pseudohypoaldosteronism. Successful treatment of the urinary tract infection was accompanied by the resolution of all hormonal and electrolyte abnormalities, including hyperaldosteronemia, hyperreninemia, hyponatremia and hyperkalemia. Radiographic examination revealed marked left dilatation of the renal pelvis and hydroureter but no vesicoureteral reflux. Owing to the possibilities of future renal scarring, decreased renal function, and hypertension, evaluation of urinary tract malformation and appropriate hormonal studies should be performed in infants with urinary tract infection and hyperkalemia.

J Nippon Med Sch 2006; 73: 289-291

Keywords
Pseudohypoaldosteronism, infant, urinary tract infection, urinary tract malformation, hypokalemia

Correspondence to
Takeshi Asano, MD, Department of Pediatrics, Chiba-Hokusoh Hospital, Nippon Medical School, 1715 Kamakari, Inba-gun, Inba-mura, Chiba 270-1894, Japan
VFF13540@nifty.ne.jp

Received, July 10, 2006
Accepted, August 10, 2006