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Journal of Nippon Medical School

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-Report on Experiments and Clinical Cases-

Quantitative Analysis of Posterior Capsule Opacification of Hydrophobic Acrylic Intraocular Lenses

Hideaki Oharazawa1, Hisaharu Suzuki1, Keiko Shibata1, Yumi Yamada1, Hironori Matsui1, Toshihiko Shiwa1, Hiroshi Takahashi1 and Kunitoshi Ohara2

1Department of Ophthalmology, Nippon Medical School
2Kichijoji Minamicho Eye Clinic, Tokyo


Posterior capsule opacification (PCO) remains a common complication of modern cataract surgery, although both modification of materials used and changes in the intraocular lens (IOL) optic edge design have helped to decrease its incidence slightly. Recently, various kinds of quantitative methods have been developed for measuring PCO. The purpose of this study was to compare the quantitative analysis of PCO between different types of IOL designs. Patients enrolled in the study had age-related cataract and underwent uneventful cataract surgery and implantation of either the AcrySof®MA30BA (Alcon) or the Sensor®AR40e (AMO), which are differently designed hydrophobic acrylic IOLs with a sharp-edged optic design. Postoperative examination was performed at 6 months. Retroillumination photographs of each eye were obtained, and the degree of PCO was assessed using the Evaluation of Posterior Capsule Opacification (EPCO) system. Grade 1 PCO was noted in both the MA30BA and the AR40e groups. There was no significant difference in the mean PCO score between the MA30BA and AR40e groups. Although the sharp-edged optic designs of both IOLs might similarly inhibit PCO at 6 months, a long-term follow-up period is needed to determine if any PCO differences occur between these 2 hydrophobic acrylic IOLs.

J Nippon Med Sch 2007; 74: 45-49

Keywords
posterior capsule opacification, Evaluation of Posterior Capsule Opacification system, sharp-edged optic design, hydrophobic acrylic intraocular lens

Correspondence to
Hideaki Oharazawa, MD, PhD, Department of Ophthalmology, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa 211-8533, Japan
hideaki@nms.ac.jp

Received, November 7, 2006
Accepted, December 12, 2006