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Journal of Nippon Medical School

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-Case Reports-

A Case of Adenosquamous Carcinoma of the Ascending Colon

Kimiyoshi Yokoi1,2, Noritake Tanaka1,2, Kiyonori Furukawa1,2, Tomoko Seya1,2, Yoshiharu Ohaki3 and Takashi Tajiri1

1Surgery for Organ Function and Biological Regulation, Graduate School of Medicine, Nippon Medical School
2Department of Surgery, Nippon Medical School Chiba Hokusoh Hospital
3Department of Pathology, Nippon Medical School Chiba Hokusoh Hospital


Adenocarcinoma accounts for most of the malignant tumors originating from the colon, whereas adenosquamous carcinoma is rare, accounting for about 0.1% of all colon cancers. We present herein a case of adenosquamous carcinoma of the ascending colon. The patient was a 94-year-old woman who presented with a chief complaint of lower abdominal pain. A barium enema examination and lower gastrointestinal endoscopy showed a type 3 tumor in the ascending colon, and a biopsy confirmed the diagnosis of adenosquamous carcinoma. Right hemicolectomy was performed, and the tumor was diagnosed as a stage III advanced colon cancer. The patient had postoperative aspiration pneumonia and died 35 days after surgery. A search of Japanese literature over the past 25 years yielded 70 patients with adenosquamous carcinoma of the colon, and the clinicopathological features are discussed herein.

J Nippon Med Sch 2008; 75: 242-246

Keywords
adenosquamous carcinoma, colon

Correspondence to
Kimiyoshi Yokoi, Department of Surgery, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inba-mura, Inba-gun, Chiba 270-1694, Japan
kimiyoko@nms.ac.jp

Received, March 14, 2008
Accepted, May 7, 2008