-Case Reports-

Transient Uptake of Thallium-201 into a Cerebral Infarction: A Case Report

Daijiro Morimoto, Daizo Yoshida, Masahiro Noha, Mitsuyoshi Sasaki, Hiroshi Takahashi and Akira Teramoto

Department of Neurosurgery, Graduate School of Medicine, Nippon Medical School

We describe a 51-year-old woman with a cerebral infarction that showed transient accumulation of thallium-201. On admission, this lesion was well-enhanced by gadolinium injection and gradually expanded, mimicking a malignant brain tumor. A cerebral angiogram, however, did not indicate the presence of a malignant brain tumor. Ethyl cysteinate dimer single photon computerized tomography showed perfusion defects throughout hospitalization. The final diagnosis of cerebral infarction was established by pathological examination. Six months after onset, the enhancement by gadolinium and the expansion of the lesion disappeared. A cerebral infarction showing transient uptake of thallium-201, and lesion expansion is indicative of a lesion in the liquefaction stage that might mimic a malignant tumor. Although thallium-201 scintigrams are useful for the differential diagnosis of radiation necrosis and recurrent brain tumor, the findings in this patient should alert clinicians to the differential diagnosis of intracerebral expansive lesions.

J Nippon Med Sch 2008; 75: 344-346

Keywords
cerebral infarction, thallium-201, inflammatory process, neuroimaging

Correspondence to
Daijiro Morimoto, MD, Department of Neurosurgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
dai_sampo@yahoo.co.jp

Received, January 16, 2008
Accepted, July 11, 2008