-Case Reports-

Basaloid Squamous Cell Carcinoma of the Esophagus: Report of Two Cases

Ichiro Akagi, Masao Miyashita, Hiroshi Makino, Tsutomu Nomura, Keiichi Ohkawa and Takashi Tajiri

Surgery for Organ Function and Biological Regulation, Graduate School of Medicine, Nippon Medical School

Basaloid squamous cell carcinoma is an uncommon malignancy of the esophagus. We present two cases of basaloid squamous carcinoma of the esophagus. Both tumors histologically consisted of solid cell nests and displayed focal immunoreactivity for type IV collagen. The nests comprised pseudoglandular structures containing myxoid matrix. Transthoracic esophagectomy with lymph node dissection was performed in both patients. The patients had uneventful postoperative courses. One patient showed no evidence of recurrence or metastasis in the 6-month postoperative period, and the other patient died of lung metastasis 28 months after the primary treatment.

J Nippon Med Sch 2008; 75: 354-360

Keywords
basaloid squamous cell carcinoma, esophagus, operation

Correspondence to
Ichiro Akagi, MD, Department of Surgery for Organ Function and Biological Regulation, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
ichiro@nms.ac.jp

Received, July 4, 2008
Accepted, August 20, 2008