-Case Reports-

Concomitant Severe Normocytic and Normochromic Anemia in Poststreptococcal Acute Glomerulonephritis

Takeshi Asano, Mariko Sudoh, Makoto Watanabe and Osamu Fujino

Department of Pediatrics, Graduate School of Medicine, Nippon Medical School
Department of Pediatrics, Nippon Medical School Chiba Hokusoh Hospital

Although anemia frequently occurs in poststreptococcal acute glomerulonephritis (PSAGN), severe anemia is rare. We report severe normocytic, normochromic anemia (hematocrit, 19.8%) in PSAGN in a 6-year-old girl with edema, macrohematuria, and proteinuria for 1 month. The potential causes of severe anemia found in this case were: 1) longer duration of massive hematuria from onset of macrohemauria to treatment, 2) a level of erythropoietin much lower than that in cases of iron deficiency anemia, and 3) hemodilution. We speculate that these factors combined to cause an unusual case of severe anemia in PSAGN.

J Nippon Med Sch 2009; 76: 272-274

Keywords
anemia, poststreptococcal acute glomerulonephritis, erythropoietin

Correspondence to
Takeshi Asano, MD, Department of Pediatrics, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inba-mura, Inba-gun, Chiba 270-1694, Japan
VFF13540@nifty.ne.jp

Received, August 5, 2009
Accepted, September 9, 2009