-Review-

Controversy of Corticosteroids in Septic Shock

Masao Miyashita

Surgery for Organ Function and Biological Regulation, Graduate School of Medicine, Nippon Medical School

The mortality rate of septic shock remains high. The guidelines of the Surviving Sepsis Campaign were published in 2004 and were revised in 2008. Steroid therapy is prominent in the guidelines but remains controversial. In this review, steroid therapy for septic shock is discussed with various landmark papers.

J Nippon Med Sch 2010; 77: 67-70

Keywords
Surviving Sepsis Campaign, corticosteroids, septic shock

Correspondence to
Masao Miyashita, MD, PhD, Department of Surgery (Division of Gastrointestinal, General, Breast and Transplantation), Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
miyashit@nms.ac.jp

Received, November 24, 2009
Accepted, January 14, 2010