-Case Reports-

Nasal Myoepithelioma Removed through Endonasal Endoscopic Surgery: A Case Report

Terumichi Fujikura^1,2 and Kimihiro Okubo¹

¹Department of Head & Neck and Sensory Organ Science, Graduate School of Medicine, Nippon Medical School
²Department of Otolaryngology, Tokyo Woman's Medical University Medical Center East

Myoepithelioma is a rare neoplasm that can occur in either the major or minor salivary gland and accounts for less than 1% of salivary gland neoplasms. We report a rare case of a nasal myoepithelioma that originated from the nasal inferior turbinate. The tumor, measuring 50 × 30 × 20 mm, was in the right nasal cavity and had a necrotic surface. We removed the tumor through endonasal endoscopic surgery. The tumor had spindle-shaped cells and was positive for cytokeratin, (AE1/AE3), vimentin, S-100β, and MIB-1 but was negative for CD34, desmin, neuron-specific enolase, and synaptophysin. Slight immunoreactivity for smooth muscle actin was noted in some tumor cells. There has been no evidence of tumor recurrence in the 18 months following surgery.

J Nippon Med Sch 2010; 77: 273-276

Keywords
myoepithelioma, nasal cavity, endoscopic surgery, cytokeratin

Correspondence to
Terumichi Fujikura, Department of Otorhinolaryngology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
teru-fujik@nms.ac.jp

Received, July 8, 2010
Accepted, August 10, 2010