-Report on Experiments and Clinical Cases-

Study of T Serotypes and Emm Genotypes of Streptococcus pyogenes in Children with Pharyngitis and Tonsillitis

Toshinari Okabe^1,2, Sachiyo Takeda^1,2, Masatoshi Hida^1,2 and Tomomi Narisada³

¹Division of Reproductive Medicine, Perinatology and Gynecologic Oncology, Graduate School of Medicine, Nippon Medical School
²Department of Pediatrics, Nippon Medical School Tama Nagayama Hospital
³Clinical Laboratory, Nippon Medical School Tama Nagayama Hospital

Streptococcus pyogenes, or group A Streptococcus (GAS), causes superficial infections of the upper respiratory tract that manifest as diseases such as pharyngitis and tonsillitis. T serotypes, emm genotypes, and the antimicrobial susceptibility of GAS isolated from the pharynges of patients with pharyngitis and tonsillitis were studied. The two most common T serotypes were T12 (10/25: 40%) and T1 (7/25: 28%), and the two most common emm genotypes were emm12 (12/27: 44%) and emm1 (7/27: 26%). Good correlation was observed between these T serotypes and emm genotypes.

J Nippon Med Sch 2011; 78: 174-177

Keywords
Streptococcus pyogenes, T serotypes, emm genotypes, pharyngitis, tonsillitis, children

Correspondence to
Toshinari Okabe, Department of Pediatrics, Nippon Medical School Tama Nagayama Hospital, 1-7-1 Nagayama, Tama, Tokyo 206-8512, Japan
tokabe@nms.ac.jp

Received, January 28, 2011
Accepted, March 9, 2011