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Journal of Nippon Medical School

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-Review-

Signal Processing in the Mammalian Retina

Makoto Kaneda

Department of Physiology, Nippon Medical School


Visual information contains many different elements, such as contrast, color, brightness, and movement. Each element is extracted from visual information in a specialized neural circuit of the retina. Finally, the extracted signals are reconstructed into coded signals at the retinal ganglion cells and sent to the higher visual center in parallel for further processing. Each specialized neural circuit has both ON- and OFF-pathways, and the signal processing in the ON-pathway is a mirror image of that in the OFF-pathway. This review focuses on the dichotomy of neural circuits in the mammalian retina.

J Nippon Med Sch 2013; 80: 16-24

Keywords
retina, bipolar cell, amacrine cell

Correspondence to
Makoto Kaneda, MD, PhD, Department of Physiology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan
mkaneda@nms.ac.jp

Received, November 29, 2012
Accepted, January 18, 2013