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Journal of Nippon Medical School

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Thoracic Aortic Aneurysms in Octogenarians: The Results of Open Surgical Repair Using Hypothermic Circulatory Arrest with Antegrade Selective Cerebral Perfusion

Ryuzo Bessho, Yôsuke Ishii, Dai Nishina and Yasuhiro Kawase

Department of Cardiothoracic Surgery, Nippon Medical School Chiba Hokusoh Hospital


Objective: Although recent progress has expanded the indications for thoracic aortic surgery to include elderly patients, the procedure remains extremely invasive. We performed a chart review to determine the early and late outcomes of thoracic aortic surgery using hypothermic circulatory arrest (HCA) and antegrade selective cerebral perfusion (ASCP) in octogenarians.
Materials and Methods: Of 79 patients who underwent surgery for thoracic aortic aneurysms from April 2007 through December 2012, 8 patients 80 years or older were selected for analysis. Mean age at the time of surgery was 84.3±1.39 years. The diagnoses were aortic dissection in 5 patients and degenerative thoracic aneurysm in 3 patients. All patients underwent surgery with HCA. The lowest body temperature was 25°C. ASCP was used as an additional brain-protection technique. Emergency operations were performed in 5 patients (62.5%).
Results: The mean duration of HCA was 60.4±19.7 minutes, that of aortic cross-clamping time was 143.0±30.4 minutes, and mean pump time was 207.8±44.4 minutes. The hospital mortality rate was 0%. Major postoperative complications occurred in 3 (37.5%) patients: stroke, temporary neurologic dysfunction, and paraparesis in 1 patient each. No patients required temporary dialysis for new-onset renal dysfunction. There were no deaths during the 65-month follow-up period.
Conclusion: The early and late outcomes after thoracic aortic surgery at our hospital using HCA with ASCP in octogenarians are acceptable. The operations are performed with an acceptable operative risk, even under emergency situations, including acute aortic dissection.

J Nippon Med Sch 2014; 81: 12-18

Keywords
thoracic aortic aneurysm, hypothermic circulatory arrest, antegrade selective cerebral perfusion, octogenarian

Correspondence to
Ryuzo Bessho, MD, PhD, Department of Cardiothoracic Surgery, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba 270-1694, Japan
r-bessho@nms.ac.jp

Received, March 6, 2013
Accepted, June 7, 2013