-Report on Experiments and Clinical Cases-

Clinical Characteristics of Pregnancies with a History of Recurrent Miscarriage at a Japanese Perinatal Center

Kayoko Terada, Kazuho Nakanishi and Shunji Suzuki

Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital

Objective: We examined obstetric and fetal/neonatal outcomes in women with a history of recurrent miscarriage.
Methods: We reviewed the obstetric records of all 5,829 nulliparous pregnant women who delivered at ≥14 weeks' gestation from 2008 through 2013 at our perinatal center. Of these women, 74 had a history of recurrent miscarriage (1.3%). The control population consisted of 4,176 nulliparous women without a history of miscarriage. Demographic information and characteristics of labor were extracted from patient charts.
Results: The rate of maternal age ≥40 years (p<0.01) and the rate of in vitro fertilization use (p<0.01) were higher in women with recurrent miscarriage than in women without miscarriage. Eleven women with recurrent miscarriage (14.9%) were treated with low-dose aspirin with and without subcutaneous heparin. In addition, the rate of cesarean delivery was higher in women with recurrent miscarriage than in women without miscarriage (p=0.02). However, fetal/neonatal outcomes did not differ significantly between the populations.
Conclusion: The pregnancy of women with a history of recurrent miscarriage is not associated with adverse outcomes at our perinatal center.

J Nippon Med Sch 2015; 82: 36-38

Keywords
perinatal outcome, pregnancy, recurrent miscarriage

Correspondence to
Shunji Suzuki, Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, 5-11-12 Tateishi, Katsushika-ku, Tokyo 124-0012, Japan
czg83542@mopera.ne.jp

Received, June 30, 2014
Accepted, August 28, 2014