-Case Reports-

A Case of Maternal Vitamin K Deficiency Associated with Hyperemesis Gravidarum: Its Potential Impact on Fetal Blood Coagulability

Daisuke Shigemi, Kazuho Nakanishi, Miwa Miyazaki, Yoshie Shibata and Shunji Suzuki

Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital

Vitamin K deficiency is associated with malnutrition in some complications, such as hyperemesis gravidarum, active gastrointestinal diseases, and psychological disorders. Maternal vitamin K deficiency can cause fetal bleeding, in particular, fetal intracranial hemorrhage. Although fetal hemorrhage is uncommon, severe damage to the fetus may be inevitable. We describe a pregnant woman with vitamin K deficiency possibly due to hyperemesis gravidarum. The patient was treated for the deficiency, and no fetal or neonatal hemorrhagic diseases were manifested.

J Nippon Med Sch 2015; 82: 54-58

Keywords
maternal vitamin K deficiency, fetal bleeding, hyperemesis gravidarum

Correspondence to
Daisuke Shigemi, Division of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, 5-11-12 Tateishi, Katsushika-ku, Tokyo 124-0012, Japan
dshigemi@nms.ac.jp

Received, May 2, 2014
Accepted, June 10, 2014