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Journal of Nippon Medical School

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-Case Reports-

Placenta with Old, Diffuse Infarction that Was Difficult to Differentiate from a Placental Tumor

Hidehiko Miyake1,2, Miwa Miyazaki-Igarashi2 and Shunji Suzuki2

1Clinical Genetics Unit, Kyoto University Hospital
2Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital


Placental lesions, including placental infarction, are associated with fetal and neonatal mortality and morbidity. We present a case of fetal growth restriction associated with an old, diffuse placental infarction. Because the placenta had only a single viable cotyledon, the others being atrophic, the lesion appeared to be a placental tumor on prenatal ultrasonography. The patient did not have pregnancy-induced hypertension. At 31 weeks of gestation, a cesarean delivery was performed because of fetal growth arrest and breech presentation. A small-for-gestational age infant was delivered with Apgar scores of 8 at both 1 and 5 minutes, and the infant had cleft palate and cleft lips. Pathological examination of the placenta revealed an old, diffuse infarction without neoplastic change. In cases in which a placental tumor causing fetal growth restriction is strongly suspected, diffuse placental infarction should be considered as part of the differential diagnosis, because placental tumors are associated with poor maternal prognosis.

J Nippon Med Sch 2015; 82: 156-158

Keywords
placental disease, fetal growth retardation, prenatal ultrasonography

Correspondence to
Hidehiko Miyake, Clinical Genetics Unit, Kyoto University Hospital, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan
hideiko@pluto.dti.ne.jp

Received, August 25, 2014
Accepted, December 17, 2014