-Case Reports-

Successful Rescue of a Patient with Acute Aconitine Poisoning Complicated by Polycystic Renal Hemorrhage

Xinguo Chen, Ruike Wu, Huanzhi Jin, Renxian Gao, Baohua Yang and Qian Wang

Department of Emergency Medicine, Wenzhou People's Hospital, China

Introduction: Aconitine is a highly toxic diterpenoid alkaloid, produced by plants of the Aconitum genus, that is still used in Chinese herbal medicines. Aconitine poisoning remains common in China and other parts of Asia.
Case Report: A 48-year-old man received a diagnosis of aconitine poisoning after ingesting herbal medicinal wine made with caowu, which is made from Aconitum kusnezoffii roots, and was admitted to our hospital's emergency department. Electrocardiography and thoracoabdominal computed tomography showed cardiovascular toxicity from aconitine poisoning along with polycystic renal hemorrhaging. Because the arrhythmia was not controlled with lidocaine, blood purification with a reduced dosage of heparin was performed to treat the arrhythmia and to avoid increasing the bleeding of the polycystic renal hemorrhage. The patient recovered from aconitine poisoning and polycystic kidney hemorrhage.
Conclusions: This case significantly advances our understanding of hemoperfusion with reduced heparin for the treatment of ventricular arrhythmia caused by aconitine poisoning.

J Nippon Med Sch 2015; 82: 257-261

Keywords
aconitine poisoning, polycystic kidney hemorrhage, blood purification

Correspondence to
Qian Wang, MD, Department of Emergency Medicine, Wenzhou People's Hospital, No 57 Changhou Street, Wenzhou 325000, China
378353790@qq.com

Received, January 8, 2015
Accepted, July 21, 2015