-Case Reports-

Primary Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma with a Nodular Opacity: Report of a Case

Naoyuki Yoshino¹, Tomomi Hirata¹, Chie Takeuchi¹, Jitsuo Usuda² and Masaru Hosone³

¹Department of Thoracic Surgery, Nippon Medical School Tama Nagayama Hospital, Tokyo, Japan
²Department of Thoracic Surgery, Nippon Medical School, Tokyo, Japan
³Department of Pathology, Nippon Medical School Tama Nagayama Hospital, Tokyo, Japan

Herein, we describe our experience in treating a case of primary pulmonary mucosa-associated lymphoid tissue lymphoma detected as a nodular opacity. A 79-year-old man was referred to our hospital. Computed tomography showed a nodular opacity measuring 20 mm in diameter with regular margins in segment 5 of the right middle lobe of the lung. Although the bronchoscopic brush cytology result was class III, the patient was tentatively diagnosed with suspected mucosa-associated lymphoid tissue lymphoma. A thoracoscopic right middle lobectomy was performed. The pathological findings showed nodular proliferation of small to medium-sized, mature-appearing atypical lymphoid cells, lymphoepithelial lesions, and vague follicles suggesting follicular colonization in some areas. The patient was diagnosed with low-grade small B-cell lymphoma and mucosa-associated lymphoid tissue lymphoma. He has remained well to date, 23 months after surgery, without evidence of recurrence.

J Nippon Med Sch 2017; 84: 87-89

Keywords
primary pulmonary lymphoma (PPL), mucosa-associated lymphoid tissue lymphoma (MALT), nodular opacity

Correspondence to
Naoyuki Yoshino, Department of Thoracic Surgery, Nippon Medical School Tama Nagayama Hospital, 1-7-1 Nagayama, Tama, Tokyo 206-8512, Japan
yoshinoy@nms.ac.jp

Received, January 26, 2016
Accepted, February 12, 2016