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Journal of Nippon Medical School

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-Short Communication-

Squamous Cell Carcinomas on Bilateral Feet Arising in Long-Standing Eczematous Lesions

Aya Yamase, Yoko Funasaka, Takashi Ueno, Michiko Ito, Yohei Otsuka, Seiji Kawana and Hidehisa Saeki

Department of Dermatology, Nippon Medical School, Tokyo, Japan


We present a woman with squamous cell carcinomas on both feet in long-standing eczematous lesions. Histopathological examination of biopsies from the both feet revealed highly atypical cells invading the reticular layer of the dermis in the hyperkeratotic lesion and they were associated with surrounding dermatitis with spongiosis. Although the cause and etiology of eczema in our case is unclear, we speculate that the exceptionally long-lasting dermatitis might have induced double SCCs on bilateral feet with an unusual constitution. To the best of our knowledge, this is a first case of SCC on bilateral feet arising in long-standing eczematous lesions.

J Nippon Med Sch 2017; 84: 105-107

Keywords
squamous cell carcinoma, bilateral feet, eczema

Correspondence to
Aya Yamase, MD, Department of Dermatology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
ayafoxy@nms.ac.jp

Received, June 15, 2015
Accepted, March 23, 2016