-Case Reports-

Endoscopic Treatment of Boerhaave Syndrome Using Polyglycolic Acid Sheets and Fibrin Glue: A Report of Two Cases

Yumiko Ishikawa¹, Takashi Tagami¹, Hayato Hirashima², Reo Fukuda¹, Yuuta Moroe¹ and Kyoko Unemoto¹

¹Department of Emergency and Critical Care Medicine, Nippon Medical School Tama Nagayama Hospital, Tokyo, Japan
²Department of Gastroenterology, Utsunomiya Memorial Hospital, Tochigi, Japan

Boerhaave syndrome, the spontaneous perforation of the esophagus, is an emergency, life-threatening condition. Current endoscopic treatment options include clipping and stenting, but the use of polyglycolic acid (PGA) sheets for treating the condition has not been reported. In recent years, PGA sheets have been used after endoscopic submucosal dissection to prevent perforations and stricture formation in patients treated for early-stage carcinoma. We report the cases of two patients with Boerhaave syndrome who were successfully treated using PGA sheets. The present clinical outcomes suggest that the use of PGA sheets is feasible and safe for treating patients with Boerhaave syndrome, and that they may be another treatment option.

J Nippon Med Sch 2017; 84: 241-245

Keywords
Boerhaave syndrome, esophageal perforation, polyglycolic acid (PGA) sheet, fibrin glue, endoscopic treatment

Correspondence to
Takashi Tagami, Department of Emergency and Critical Care Medicine, Nippon Medical School Tama Nagayama Hospital, 1-7-1 Nagayama, Tama, Tokyo 206-8512, Japan
t-tagami@nms.ac.jp

Received, May 12, 2017
Accepted, July 19, 2017