-Short Communication-

A Case of Microscopic Polyangiitis with Subarachnoid Hemorrhage and Cardiovascular Complications

Sae Aratani, Yukinao Sakai and Shuichi Tsuruoka

Department of Nephrology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan

Microscopic polyangiitis (MPA) is a primary systemic vasculitis that predominantly affects small and medium vessels. MPA is rarely complicated with central nervous system or cardiovascular disease.
We report a very rare case of MPA complicated with cerebral infarction, cardiovascular disease, and fatal subarachnoid hemorrhage in a 54-year-old man. During the first six days of hospitalization the patient was diagnosed with rapid progressive glomerulonephritis (RPGN), cerebral infarction, and unstable angina. According to patient's symptoms and laboratory findings, were consisted with a diagnosis of severe MPA. Steroid pulse therapy was immediately introduced. However, the patient developed massive subarachnoid hemorrhage on the 8th day of hospitalization. The condition progressively deteriorated, and the patient died on the 33rd hospital day.

J Nippon Med Sch 2017; 84: 251-255

Keywords
microscopic polyangiitis, cerebral infarction, unstable angina, subarachnoid hemorrhage

Correspondence to
Sae Aratani, Department of Nephrology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
sae-aratani@nms.ac.jp

Received, September 30, 2015
Accepted, February 9, 2016