-Case Reports-

An 8-Year-Old Girl with Autoimmune Hepatitis Following Aplastic Anemia

Ayako Nishigori¹, Tsutomu Hatori² and Takeshi Asano¹

¹Department of Pediatrics, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan
²Department of Pathology, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan

We herein report a case of severe aplastic anemia diagnosed in an 8-year-old girl with a previous diagnosis of autoimmune hepatitis. We found significantly increased CD8+ and CD68+ cell numbers in her bone marrow, which can induce severe organ damage, refractory to immunosuppressive therapy.

J Nippon Med Sch 2018; 85: 241-244

Keywords
autoimmune hepatitis, aplastic anemia, macrophage, child

Correspondence to
Takeshi Asano, MD, Department of Pediatrics, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba 270-1694, Japan
july1364@nms.ac.jp

Received, February 7, 2018
Accepted, March 6, 2018