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Journal of Nippon Medical School

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-Case Reports-

A Patient with Primary Open-Angle Glaucoma with Re-Elevated Nocturnal Sitting Intraocular Pressure after Restarting Medical Therapy due to a Bleb Failure

Kenji Nakamoto, Naka Shiratori, Yusuke Nishio, Shio Sugimoto, Yasuko Takano, Masashi Yamazaki, Yutaro Tobita, Tsutomu Igarashi and Hiroshi Takahashi

Department of Ophthalmology, Nippon Medical School, Tokyo, Japan


We describe the case of a primary open-angle glaucoma patient with re-elevated nocturnal sitting intraocular pressure (IOP) after restarting medical therapy due to a failing bleb. IOP was markedly higher than diurnal IOP during multiple-drug therapy in both eyes, but it did not increase in the left eye with a functional bleb without medical therapy after trabeculectomy with adjuvant mitomycin. However, nocturnal sitting IOP was re-elevated after restarting multiple-drug therapy due to a failing bleb, while diurnal IOP was maintained at a low level.

J Nippon Med Sch 2021; 88: 509-511

Keywords
24-hour intraocular pressure, trabeculectomy, diurnal intraocular pressure variation, nocturnal intraocular pressure, glaucoma

Correspondence to
Kenji Nakamoto, MD, Department of Ophthalmology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan
user902850@aol.com

Received, November 8, 2020
Accepted, December 15, 2020