-Review-

Neuroprotection during Open Aortic Arch Surgery: Cerebral Perfusion Methods and Temperature

Ryuzo Bessho

Department of Cardiovascular Surgery, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan

Neuroprotection is important in open aortic arch surgery because of the dependence of brain tissues on cerebral perfusion. Therefore, several techniques have been developed to reduce cerebral ischemia and improve outcomes in open aortic arch surgery. In this review, I describe various neuroprotective strategies, such as profound and deep hypothermic circulatory arrest, selective antegrade cerebral perfusion, retrograde cerebral perfusion, and lower body circulatory arrest; compare their advantages and disadvantages, and discuss their evolution and current status by reviewing relevant literature.

J Nippon Med Sch 2023; 90: 11-19

Keywords
aortic arch, neuroprotection, cerebral perfusion, body temperature, cerebral ischemia

Correspondence to
Ryuzo Bessho, MD, PhD, Department of Cardiovascular Surgery, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba 270-1694, Japan
r-bessho@nms.ac.jp

Received, February 21, 2022
Accepted, April 21, 2022