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Journal of Nippon Medical School

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-Case Reports-

Takotsubo Cardiomyopathy Presenting with QT Prolongation and Torsade de Pointes in a Patient with Coronavirus Disease 2019

Hidekazu Kawanaka1, Michio Ogano1, Keita Hibako2 and Jun Tanabe1

1Department of Cardiovascular Medicine, Shizuoka Medical Center, Shizuoka, Japan
2Department of Emergency Medicine, Shizuoka Medical Center, Shizuoka, Japan


Coronavirus disease 2019 (COVID-19) is associated with cardiovascular complications; however, Takotsubo cardiomyopathy (TCM) with QT prolongation and Torsade de pointes has been reported only rarely. We present a case of TCM after QT prolongation and Torsade de pointes. A 58-year-old woman was admitted because of COVID-19-related pneumonia. Seven days after admission, she developed sudden loss of consciousness without any indication of cardiovascular disease. A monitoring electrocardiogram indicated Torsade de pointes and a prolonged QT interval. Emergency cardiac catheterization revealed TCM. She was treated with favipiravir and steroids, followed by rehabilitation, and her condition improved. To detect asymptomatic TCM, routine electrocardiography screening should be considered for patients with COVID-19.

J Nippon Med Sch 2024; 91: 124-128

Keywords
COVID-19, Takotsubo cardiomyopathy, QT prolongation, Torsade de pointes, pacing

Correspondence to
Michio Ogano, MD, Department of Cardiovascular Medicine, Shizuoka Medical Center, 762-1 Nagasawa, Shimizu, Sunto, Shizuoka 411-0906, Japan
m-ogano@nms.ac.jp

Received, July 1, 2022
Accepted, September 28, 2022