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Journal of Nippon Medical School

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Effect of the COVID-19 Pandemic on the Mental Status of Pregnant Women: A Single-Center Study

Asako Watanabe1, Kei Sagawa1, Eika Harigane1, Hiroki Shinmura1, Ryuhei Kurashina1, Takashi Matsushima1 and Shunji Suzuki2

1Department of Obstetrics and Gynecology, Nippon Medical School Musashi Kosugi Hospital, Kanagawa, Japan
2Department of Obstetrics and Gynecology, Nippon Medical School Hospital, Tokyo, Japan


Background: The coronavirus disease 2019 (COVID-19) pandemic has forced people to make major life changes, and there is concern that depressive tendencies have increased in pregnant women during the pandemic. This study used the Edinburgh Postnatal Depression Scale (EPDS), administered in the second trimester, to investigate the effect of COVID-19 on the mental health of Japanese women during pregnancy and to provide early intervention.
Methods: The study included 1,320 pregnant women (663 pre-COVID-19 and 657 during COVID-19) with similar background characteristics and compared the results for the COVID-19 period (September 2020-August 2021) and control period (September 2018-August 2019). Women treated for psychiatric disorders were excluded. The EPDS cutoff score was 13.
Results: The median EPDS scores were 3 (1-6) points during the control period and 3 (1-5) points during the pandemic (p = 0.166) for the control and pandemic periods. Fourteen patients (2.1%) during the control period and 20 (3.0%) during the pandemic scored ≥13 points; however, the difference was not significant (odds ratio, 1.455; 95% confidence interval: 0.692-3.143).
Conclusions: COVID-19 did not change mid-pregnancy EPDS scores at a single Japanese center.

J Nippon Med Sch 2024; 91: 457-464

Keywords
COVID-19 pandemic, Edinburgh Postnatal Depression Scale (EPDS), mental health, second trimester, depression

Correspondence to
Asako Watanabe, Department of Obstetrics and Gynecology, Nippon Medical School Musashi Kosugi Hospital, 1-383 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa 211-8533, Japan
morning1024@nms.ac.jp

Received, September 29, 2023
Accepted, July 12, 2024