第13巻 2017年4月　第2号

■臨床および実験報告

エキシマライト照射とビタミンD₃外用の併用が有効であったSjögren症候群を合併した尋常性白斑の1例
大塚　流音, 船坂　陽子, 佐伯　秀久
日本医科大学皮膚科

A Case of Vitiligo Vulgaris Associated with Sjögren Syndrome Successfully Treated with Excimer Light Irradiation and Topical Vitamin D₃
Rui Otsuka, Yoko Funasaka and Hidehisa Saeki
Department of Dermatology, Nippon Medical School

A 72-year-old Japanese woman presented in July 2012 with a 5-year history of depigmented areas on the face. On physical examination, she had multiple well-demarcated depigmented areas on the face and neck. She had also experienced increased thirst for the past 3 years. A blood sample was positive for antinuclear and anti-SS-A antibodies. A biopsied specimen from the lower lip showed dense focal lymphoid infiltration in the minor salivary glands. The patient was diagnosed with vitiligo vulgaris associated with Sjögren syndrome. Internal treatment with L-cysteine, tocopherol nicotinate and topical tacrolimus was of limited efficacy. Subsequent excimer light irradiation together with topical vitamin D₃ administration led to repigmentation around the hair follicles without causing photodermatosis. These treatments appear to be effective for patients with vitiligo vulgaris associated with Sjögren syndrome who have no past history of photosensitivity.

日医大医会誌 2017; 13(2), 97-100

Key words
vitiligo vulgaris, Sjögren syndrome, anti SS-A antibody, excimer light, topical vitamin D₃

Correspondence to
Rui Otsuka, Department of Dermatology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku Tokyo 113-8603, Japan
E-mail：ruirui0125cherry@nms.ac.jp

受付：2017年1月8日　受理：2017年1月25日