■論説
臨床現場における薬剤師の役割（14）―ピモベンダン投与患者における，GDMT強化の有効性について
岩出 佳樹1, 久保田 芳明2, 伊勢 雄也1, 淺井 邦也2
1日本医科大学付属病院薬剤部
2日本医科大学付属病院循環器内科
The Role of the Pharmacist in Clinical Settings (14): The Effectiveness of GDMT Reinforcement in Patients Receiving Pimobendan
Yoshiki Iwade1, Yoshiaki Kubota2, Yuya Ise1 and Kuniya Asai2
1)Department of Pharmaceutical Service, Nippon Medical School Hospital
2)Department of Cardiovascular Medicine, Nippon Medical School Hospital
Heart failure is a critical global public health issue, significantly impacting patients' quality of life and healthcare costs. In Japan, heart diseases rank among the leading causes of death, highlighting the urgent need for effective treatment strategies for heart failure patients. In recent years, guideline-directed medical therapy (GDMT) has been increasingly recommended, with particular focus on the use and optimization of specific therapeutic agents. Our study demonstrated that the reinforcement of GDMT in heart failure patients receiving pimobendan may contribute to a reduction in rehospitalization rates. This effect was particularly pronounced in patients with reduced ejection fraction (rEF), emphasizing the pivotal role of GDMT in heart failure management. This article explores the impact of the combination of pimobendan and GDMT on the prognosis of patients with heart failure.
日医大医会誌 2025; 21(2), 170-174
Key words
heart failure, pimobendan, GDMT
Correspondence to
Yoshiki Iwade, Department of Pharmaceutical Service, Nippon Medical School Hospital, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
E-mail：y-iwade@nms.ac.jp
受付：2024年12月24日 受理：2025年2月27日 |
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