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ArticleTitle | The short-term effects of tamsulosin in Japanese men with benign prostatic hyperplasia |
AuthorList | Kazutaka Horiuchi, Narumi Tsuboi, Tomotaka Hattori, Kazuhiro Yoshida and Masao Akimoto |
Affiliation | Department of Urology, Nippon Medical School |
Language | EN |
Volume | 66 |
Issue | 6 |
Year | 1999 |
Page | 382-387 |
Received | July15,1999 |
Accepted | September16,1999 |
Keywords | prostate, benign prostatic hyperplasia, clinical effect, tamsulosin |
Abstract | We evaluated the short-term effects of tamsulosin in treating benign prostatic hyperplasia. Twenty-seven patients, aged57to86years(mean68.4), complaining of obstructive urinary symptoms who had received no previous treatment for such symptoms were orally administered0.2mg of tamsulosin for4weeks. Symptoms(total AUA symptom score and AUA symptom subscores)and objective parameters including peak and average flow rate, and post-void residual urine rate were evaluated before and after1,2and4weeks of treatment. The mean total AUA symptom score and the mean AUA symptom subscores for incomplete emptying and weak stream were significantly decreased after only1week of treatment. The mean AUA symptom subscores for intermittency, urgency and nocturia were significantly decreased after4weeks of treatment. The mean AUA symptom subscores for frequency and hesitancy were unchanged after4weeks of treatment. The mean peak and average flow rate, and post-void residual urine rate were significantly improved after only1week of treatment. In conclusion, tamsulosin improved not only objective parameters but also symptoms only1week after the start of treatment. |
Correspondence to | Kazutaka Horiuchi, Department of Urology, Nippon Medical School,1-1-5Sendagi, Bunkyo-ku, Tokyo113-8603, Japan |
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