-Case Reports-

Successful Use of Endoscopic Argon Plasma Coagulation for Patients with Early Gastric Cancer and Diabetes Mellitus

Masao Ogata¹, Kentaro Maejima¹, Naoto Chihara¹, Satoshi Mizutani¹, Osamu Komine¹, Hideki Bo¹, Takeshi Shioya¹, Masanori Watanabe¹, Akira Tokunaga¹ and Takashi Tajiri²

¹Institute of Gastroenterology, Nippon Medical School Musashi Kosugi Hospital
²Surgery for Organ Function and Biological Regulation, Graduate School of Medicine, Nippon Medical School

We report on two patients with gastric tumors (early cancer and adema) and diabetes mellitus who were treated with argon plasma coagulation (APC) therapy. Case 1. A 78-year-old woman visited the Nippon Medical School Musashi Kosugi Hospital because of epigastric pain. An early gastric cancer (IIc) in the anterior wall of the gastric antrum was diagnosed on the basis of the results of a gastric endoscopy examination. The patient had had diabetes mellitus for 18 years and had injected insulin (NovoRapid 30 Mix^®, 72 units/day) by herself everyday for 10 years. Case 2. A 61-year-old man was referred to our hospital because of a gastric tumor. A gastric adenoma in the anterior of the gastric antrum was diagnosed on the basis of the results of a gastric endoscopy examination. The patient had had diabetes mellitus for 12 years and had been taking oral medication for 2 years. Endoscopic APC was performed in both patients to remove the gastric tumors. These patients have been well for 28 months and 30 months, respectively, after undergoing APC treatment. APC therapy appears to be a safe and useful treatment for patients with diabetes and gastric mucosal lesions.

J Nippon Med Sch 2007; 74: 246-250

Keywords
early gastric cancer, gastric adenoma, diabetes mellitus, argon plasma coagulation

Correspondence to
Masao Ogata, MD, Institute of Gastroenterology, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa 211-8533, Japan
masao@nms.ac.jp

Received, February 19, 2007
Accepted, April 18, 2007