-Case Reports-

Successful Treatment of Gastroparesis with the Antidepressant Mirtazapine: A Case Report

Junmin Song¹, Nan Lin², Feng Tian¹, Yang Li³ and Yan Li¹

¹Department of Gastroenterology, Shengjing Hospital of China Medical University, China
²Department of Radiology, Shengjing Hospital of China Medical University, China
³Department of Intensive Care Unit, Shengjing Hospital of China Medical University, China

Treatments for gastroparesis have been unsatisfactory. We describe a patient with gastroparesis who did not respond to a series of conventional prokinetic treatments. Finally, an antidepressant, mirtazapine, was administered, and the patient's symptoms and gastric emptying showed surprisingly rapid improvement. Therefore, we recommend mirtazapine as a treatment for gastroparesis refractory to conventional treatments.

J Nippon Med Sch 2014; 81: 392-394

Keywords
gastroparesis, mirtazapine, antidepressant

Correspondence to
Junmin Song, Department of Gastroenterology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang, Liaoning 110004, People's Republic of China
songdoctor@sina.com

Received, April 1, 2014
Accepted, May 8, 2014