Home > List of Issue > Table of Contents > Abstract
![]() |
![]() |
|||||
Select Language in Japanese < > in English |
|
ArticleTitle | Plasma Immunoadsorption Therapy for Guillain-Barré Syndrome: Critical Day for Initiation |
AuthorList | Hiroyuki Takei1, Yuichi Komaba1, Toshihiko Araki2,Yasuhiko Iino1 and Yasuo Katayama1 |
Affiliation | 1Second Department of Internal Medicine, Nippon Medical School, 2Department of Neurology, Kawaguchi Municipal Medical Center, Saitama |
Language | EN |
Volume | 69 |
Issue | 6 |
Year | 2002 |
Page | 557-563 |
Received | January 7, 2002 |
Accepted | July 18, 2002 |
Keywords | immunoadsorption plasmapheresis, Guillain-Barré syndrome, timing of therapy, clinical improvement, regression analysis |
Abstract |
Immunoadsorption plasmapheresis (IAPP) is a method of removing circulating immune factors that is used to treat Guillain-Barré syndrome (GBS). We retrospectively analyzed the data on our GBS patients. In 21 patients treated with IAPP, linear regression analysis showed that the time from the onset of symptoms to the initiation of IAPP was correlated with the time required for improvement by one Hughes functional grade. We investigated the critical day for initiating treatment, which we defined as the day when initiation of IAPP was significantly more likely to improve function by at least one Hughes grade when compared with the outcome in patients receiving supportive therapy (non-IAPP group). The critical day was found to be day 6 after the onset of GBS. |
Correspondence to | Hiroyuki Takei, MD, Second Department of Internal Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan h-tokei@SC4.so-net.ac.jp |
Copyright © The Medical Association of Nippon Medical School