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ArticleTitle	Clinical Analysis of 22 cases with Syphilis Racenta in Department of Dermatology, Nippon Medical School
AuthorList	Izumi Kikuchi, Mikako Aoki, Toichi Kitahara and Seiji Kawana
Affiliation	Department of Dermatology, Nippon Medical School
Language	JA
Volume	70
Issue	3
Year	2003
Page	274-277
Received	September 4, 2002
Accepted	December 25, 2002
Keywords	syphilis, syphilis recenta, clinical statistical analysis
Abstract	Forty-nine patients with syphilis were seen from January 1996, to June 2000 at the Dermatological Clinic of Nippon Medical School Hospital. The frequency of syphilis among all outpatients was 0.17%, and the number of male syphilis patients was almost twice that of female syphilis patients. Many sexual contacts (especially with female prostitutes) were considered to be the source of the infection in a large proportion of the syphilis patients. Chancres were observed in 50% of the 6 patients with primary syphilis. Macular or papular syphilide and psoriasis syphilitica were the most frequently observed symptoms in the patients with secondary syphilis. The Jarisch-Herxheimer reaction was observed in 18.8%. The titer of IgM-TPHA responded well to the therapy, and decreased or even disappeared after treatment. The titer of TPHA did not change markedly upon treatment. A retrospective study of syphilis from 1980 revealed that the incidence of syphilis, especially early infectious syphilis, in patients at our clinic has decreased markedly since 1991.
Correspondence to	Izumi Kikuchi, Department of Dermatology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan ogy@nms.ac.jp