Journal of Nippon Medical School: Vol.70 No.3 page.274

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ArticleTitle 日本医科大学付属病院における顕症梅毒の検討

AuthorList 菊地伊豆実, 青木見佳子, 北原東一, 川名誠司

Affiliation 日本医科大学皮膚科教室

Language JA

Volume 70

Issue 3

Year 2003

Page 274-277

Received September 4, 2002

Accepted December 25, 2002

Keywords syphilis, syphilis recenta, clinical statistical analysis

Abstract Forty-nine patients with syphilis were seen from January 1996, to June 2000 at the Dermatological Clinic of Nippon Medical School Hospital. The frequency of syphilis among all outpatients was 0.17%, and the number of male syphilis patients was almost twice that of female syphilis patients.
Many sexual contacts (especially with female prostitutes) were considered to be the source of the infection in a large proportion of the syphilis patients. Chancres were observed in 50% of the 6 patients with primary syphilis. Macular or papular syphilide and psoriasis syphilitica were the most frequently observed symptoms in the patients with secondary syphilis. The Jarisch-Herxheimer reaction was observed in 18.8%. The titer of IgM-TPHA responded well to the therapy, and decreased or even disappeared after treatment. The titer of TPHA did not change markedly upon treatment. A retrospective study of syphilis from 1980 revealed that the incidence of syphilis, especially early infectious syphilis, in patients at our clinic has decreased markedly since 1991.

Correspondence to Izumi Kikuchi, Department of Dermatology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
ogy@nms.ac.jp

ArticleTitle	日本医科大学付属病院における顕症梅毒の検討
AuthorList	菊地伊豆実, 青木見佳子, 北原東一, 川名誠司
Affiliation	日本医科大学皮膚科教室
Language	JA
Volume	70
Issue	3
Year	2003
Page	274-277
Received	September 4, 2002
Accepted	December 25, 2002
Keywords	syphilis, syphilis recenta, clinical statistical analysis
Abstract	Forty-nine patients with syphilis were seen from January 1996, to June 2000 at the Dermatological Clinic of Nippon Medical School Hospital. The frequency of syphilis among all outpatients was 0.17%, and the number of male syphilis patients was almost twice that of female syphilis patients. Many sexual contacts (especially with female prostitutes) were considered to be the source of the infection in a large proportion of the syphilis patients. Chancres were observed in 50% of the 6 patients with primary syphilis. Macular or papular syphilide and psoriasis syphilitica were the most frequently observed symptoms in the patients with secondary syphilis. The Jarisch-Herxheimer reaction was observed in 18.8%. The titer of IgM-TPHA responded well to the therapy, and decreased or even disappeared after treatment. The titer of TPHA did not change markedly upon treatment. A retrospective study of syphilis from 1980 revealed that the incidence of syphilis, especially early infectious syphilis, in patients at our clinic has decreased markedly since 1991.
Correspondence to	Izumi Kikuchi, Department of Dermatology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan ogy@nms.ac.jp