基礎医学

2017

Ishii H, Hattori Y, Munetomo A, Watanabe H, Sakuma Y, Ozawa H.: Characterization of rodent constitutively active estrogen receptor α variants and their constitutive transactivation mechanisms.

Gen Comp Endocrinol. 248 : 16-28 (2017)

Iwata K., Kunimura Y., Matsumoto K., Ozawa H.: Effect of Androgen on Kiss1 Expression and Luteinizing Hormone Release in Female Rats. Journal of Endocrinology. 233 : 281-292 (2017)

Higo S., Iijima N., Ozawa H. "Characterization of Kiss1r (Gpr54)-expressing neurons in the arcuate nucleus of the female rat hypothalamus", Journal of Neuroendocrinology. (2017)

Tomori Y, Takumi K, Iijima N, Takai S, Ozawa H. "Kisspeptin expression is decreased in the arcuate nucleus of hypothyroid female rats with irregular estrus cycles", Neuroscience Research. (2017)

Kunimura Y, Iwata K, Ishigami A, Ozawa H. "Age-related alterations in hypothalamic kisspeptin, neurokinin B, and dynorphin neurons and in pulsatile LH release in female and male rats", Neurobiology of Aging 19 (2017) 30-38

2016

Yujiro Hattori, Hirotaka Ishii, Arisa Munetomo, Hiroshi Watanabe, Akio Morita, Yasuo Sakuma, Hitoshi Ozawa, Human C-terminally truncated ERα variants resulting from the use of alternative exons in the ligand-binding domain. Molecular and Cellular Endocrinology, 425:111-22 (2016).

Iwata K.,Ikehara M.,Kunimura Y.,Ozawa H.: Interactions between Kisspeptin Neurons and Hypothalamic Tuberoinfundibular Dopaminergic Neurons in Aged Female Rats. Acata Histochemica et Cytochemica. 49. 191-196.( 2016)

Nagamoto, S., Iijima, N., Ishii, H., Takumi, K., Higo, S., Aikawa, S., Anzai, M., Matsuo, I., Nakagawa, S., Takashima, N., Shigeyoshi, Y., Sakamoto, A., Ozawa, H. "Establishment of an in vitro cell line experimental system for the study of inhalational anesthetic mechanisms", Neurosci Lett 620 (2016) 163-168.

Murakawa, H., Iwata, K., Takeshita, T., Ozawa, H. "Immunoelectron microscopic observation of the subcellular localization of kisspeptin, neurokinin B and dynorphin A in KNDy neurons in the arcuate nucleus of the female rat", Neurosci Lett 612 : 161-166.(2016)

Matsuo, I., Iijima, N., Takumi, K., Higo, S., Aikawa, S., Anzai, M., Ishii, H., Sakamoto, A., Ozawa, H. "Characterization of sevoflurane effects on Per2 expression using ex vivo bioluminescence imaging of the suprachiasmatic nucleus in transgenic rats", Neurosci Res 107 : 30-37. (2016)

Li, S., Takumi, K., Iijima, N., Ozawa, H. "The increase in the number of spines on the gonadotropin-releasing hormone neuron across pubertal development in rats", Cell Tissue Res 364 : 405-414 (2016).

Higo, S., Honda, S., Iijima, N., Ozawa, H. "Mapping of Kisspeptin Receptor mRNA in the Whole Rat Brain and its Co-Localisation with Oxytocin in the Paraventricular Nucleus", J Neuroendocrinol 28 (2016).

2015

Takumi, K., Shimada, K., Iijima, N., Ozawa, H. "Maternal high-fat diet during lactation increases Kiss1 mRNA expression in the arcuate nucleus at weaning and advances puberty onset in female rats", Neurosci Res 100 : 21-28.(2015)

Kunimura, Y., Iwata, K., Iijima, N., Kobayashi, M., Ozawa, H. "Effect of sex steroid hormones on the number of serotonergic neurons in rat dorsal raphe nucleus", Neurosci Lett 594 : 127-132. (2015)

Higo, S., Aikawa, S., Iijima, N., Ozawa, H. "Rapid modulation of hypothalamic Kiss1 levels by the suckling stimulus in the lactating rat" J Endocrinology 227 :105-115.(2015)

Hattori, Y., Ishii, H., Morita, A., Sakuma, Y., Ozawa, H. "Characterization of the fundamental properties of the N-terminal truncation (Delta exon 1) variant of estrogen receptor alpha in the rat", Gene 571:117-125. (2015)

2014

Mori K., Iijima N., Higo S., Aikawa S., Matsuo I., Takumi K., Sakamoto A., Ozawa H.: Epigenetic Suppression of Mouse Per2 Expression in the Suprachiasmatic Nucleus by the lnhalational Anesthetic , Sevoflurane. PLOS ONE : Volume9 (1) e87319 (2014)

2013

Anzai M., Iijima N., Higo S., Takumi K., Matsuo I., Mori K., Ohe Y., Kadota K., Akimoto T., Sakamoto A., Ozawa H.: Direct and Specific Effect of Sevoflurane Anesthesia on rat Per2 Expression in the Suprachiasmatic Nucleus. PLOS ONE : Volume8 (3) e59454 (2013)

2012

Takumi K., Iijima N., Higo S., Ozawa H. :Immunohistochemical analysis of the colocalization of corticotropin-releasing hormone receptor and glucocorticoid receptor in kisspeptin neurons in the hypothalamus of female rats. Neuroscience Letters.531:40-45(2012)

Kadota K., Iijima N., Ohe-Hayashi Y., Takui K., Higo S., Sakamoto A., Ozawa H.: Time-dependent repression of mPer2 expression in the suprachiasmatic nucleus by inhalation anesthesia with sevoflurane. Neuroscience Letters 528:153-158(2012)

Takumi K., Iijima N., Iwata K., Higo S., Ozawa H. : The effects of gonadal steroid manipulation on the expression of Kiss1 mRNA in rat arcuate nucleus during postnatal development. J. Physiol Sci. 62:453-460(2012)

Ozawa H., Sawai N., Iwata K., Takumi K., Iijima N. : Regulation of tubero- infundibular dopamine (TIDA) neurons by kisspeptin neurons. J Nippon Med Sch. 79 :168-9 (2012)

Sawai N., Iijima N., Takumi K., Matsuzaki T., Ozawa H : Immunofluorescent histochemical and ultrastractural studies on the innervation of kisspeptin/ neurokinin B neurons to tuberoinfundibular dopaminergic neurons in the arcuate nucleus. Neurosci Res 74 : 10-16 (2012)

Yamazaki C., Nagano M., Sujino M., Kubo, A, Terashima T., Ozawa H., Shigeyoshi Y :Application of layer-specific markers in the evaluation of abnormal cytoarchitecture in the olfactory bulb of prokineticin receptor 2 deficient mice. Acta Med Kinki Univ 37 : 35-43 (2012)

Yang C-Y., Matsuzaki T., Iijima N., Kajimura N., Ozawa H.:Morphofunctional Changes of the Astrocyte in Rat Hippocampus Under Different Corticosteroid Conditions. Medical Molecular Morphology 45:206-213 (2012)

2011

Matsuzaki T., Inahata Y., Sawai N.,Yang C-Y., Kobayashi M., Takata K.,Ozawa H.: Immunohistochemical localization of water channels, AQP4 and AQP5 in the rat pituitary gland. Acta Histochem Cytochem 44(6):259~266(2011)

Tobari Y., Iijima N., Tsunekawa K., Osugi T., Haraguchi S., Ubuka T., Ukena K., Okanoya K., Tsutsui K., Ozawa H.: Identification, Localisation and Functional lmplication of 26RFa

Orthologue Peptide in the Brain of Zebra Finch (Taeniopygia guttata). J.Neuroendocrinol. 23:791-803(2011)

Iijima N., Takumi K., Sawai N., Ozawa H. : An immunohistochemical study on the exressional dynamics of kisspeptin neurons relevant to GnRH neurons using anewly developed anti-kisspeptin antibody. Journal of Molecular Neruoscience 43:146-154(2011)

Ohe Y., Iijima N., Kadota K., Sakamoto A., Ozawa H.: The general anesthetic sevoflurane affects the expression of clock gene mPer2 accompanying the change of NAD+ level in the suprachiasmatic nucleus of mice. Neuroscience Letters 490:231-236 (2011)

2010

Akimoto T., Terada M., Shimizu A., Sawai N., Ozawa H. : The influence of dietary restriction on the development of diabetes and pancreatitis in female WBN/Kob-fatty rats. Experimental Animals 59:623-630(2010)

Yoshimoto M., Yamamoto N. : Ascending general visceral sensory pathway from the brainstem to the forebrain in a cichlid fish, oreochromis (tilapia) niloticus. The Journal of Comparative Neurology 518 : 3570-3603 (2010)

Tobari Y., Iijima N., Tsunekawa K., Osugi T., Okanoya K., Tsutsui K., Ozawa H.: Identification of gonadotropin-inhibitory hormone in the zebra finch (Taeniopygia guttata) : Peptide isolation, cDNA cloning and brain distribution. Peptides. 31(5):816-826 (2010)

Sawai N., Ueta Y., Nakazato M., Ozawa H. : Developmental and aging change of orexin-A and -B immunoreactive neurons in the male rat hypothalamus. Neurosci Letter 468(1):51-55 (2010)

2009

Okabe T., Sato C., Matsumoto K., Hitoshi Ozawa., Sakamoto A.: Elecroconvulsive stimulation (ECS) increases the expression of neuropeptideY (NPY) in rat brain in a model of neuropathic pain : A quantitative real-time polymerase chain reaction (RT-PCR) study. Pain Medicine 10 (8) : 1460-1467 (2009)

Matsuzaki T., Hata H., Ozawa H., Takata K.: Immunohistochemical localization of the aquaporins AQP1, AQP3, AQP4 and AQP5 in the mouse respiratory system Acta Histochem Cytochem 42 (6) : 159-169 (2009)

Iida Y., Matsuzaki T., Morishima T., Sasano H., Asai K., Sobue K., Takata K.: Localization of reversion-induced LIM protein (RIL) in the rat central nervous system. Acta Histochem Cytochem 42(1):9-14. (2009)

2008

Yoshii T., Sakamoto H., Kawasaki M., Ozawa H., Ueta Y., Onaka T., Fukui K., Kawata M.: The single-prolonged stress paradigm alters both the morphology and stress response of magnocellular vasopressin neurons. Neuroscience 156(3):466-474. (2008)

Yasuda T., Yoshimoto M., Maeda K., Matsumoto A., Maruyama K., Ishikawa Y.: Rapid and simple method for quantitative evaluation of neurocytotoxic effects of radiation on developing medaka brain. Journal of Radiation Research 49(5):533-540.(2008)

Aoki S., Tanuma K., Iwakiri I., Mizuno H., Ogawa R., Ozawa H., Hyakusoku H.: Clinical and vascular anatomical study of distally based sural flap. Annals of Plastic Surgery 61(1):73-78. (2008)

Nagano M., Ozawa H., Suzuki H.: Prenatal dexamethasone exposure affects anxiety-like behaviour and neuroendocrine systems in an age-dependent manner. Neuroscice Res. 60(4):355-460. (2008)

Ishikawa Y., Yasuda T., Kage T., Takashima S., Yoshimoto M., Yamamoto N., Maruyama K., Takeda H., Ito H.: Early development of cerebellum in teleost fish: A study based on gene expression pattern and histology in medaka embryo. Zoological Science 25:407-418. (2008)

Xue H-G., Yang C-Y., Yamamoto N.: Afferent sources to the inferior olive and distribution of the olivocerebellar climbing fibers in cyprinids. The Journal of Comparative Neurology 507(3):1409-1427. (2008)

Akimoto T., Nakama K., Katsuta Y., Zhang X-J., Ishizaki M., Sawai N., Ozawa H.: Characterization of a novel congenic strain of diabetic fatty (WBN/Kob-Leprfa) rat. Biochemical and Biophysical Research Communications 366(2):556-562. (2008)

Yang C-Y., Xue H-G., Tanuma K., Ozawa H.: Variations of the bilateral testicular veins: embryological and clinical considerations. Surgical and Radiological Anatomy 30(1):53-55 (2008).

2007

Xue H-G., Yang C-Y., Asagawa M., Tanuma K., Ozawa H.: Duplication of inferior vena cava associated with other variations. Anatomical Science International 82(2):121-125 .(2007)

Yang C-Y., Xue H-G., Yoshimoto M., Ito H., Yamamoto N., Ozawa H.: Fiber connections of the corpus glomerulosum pars rotunda, with special reference to efferent projection pattern to the inferior lobe in a percomorph teleost, tilapia (Oreochromis niloticus). The Journal of Comparative Neurology 501(4):582-607.(2007)

Vinh VQ., Ogawa R., Iwakiri I., Hyakusoku H., Tanuma K.: Clinical and anatomical study of cervico-pectoral(CP) “super- thin flap”. Plastic and Reconstructive Surgery 119(5):1464-1471.(2007)

Shibata M., Fujihara H., Suzuki H., Ozawa H., Kawata M., Dayanithi G., Murphy D., Ueta T.: Physiological studies of stress responses in the hypothalamus of vasopressin-enhanced green fluorescent protein transgenic rat. Journal of Neuroendocrinology 19(4):285-292.(2007)

Xue H-G., Yang C-Y., Yamamoto N., Ozawa H.: Fiber connections of the periventricular pretectal nucleus in a teleost, tilapia (Oreochromis niloticus). Neuroscience Research 57(2):184-193.(2007)

Han F., Ozawa H., Matsuda KI., Lu H., De Kloet ER., Kawata M.: Changes in the expression of corticotrophin-releasing hormone, mineralocorticoid receptor and glucocorticoid receptor mRNAs in the hypothalamic paraventricular nucleus induced by fornix transection and adrenalectomy. Journal of Neuroendocrinology 19(4):229-238.(2007)

Nagae M., Ikeda T., Mikami Y., Hase H., Ozawa H., Matsuda KI., Sakamoto H., Tabata Y., Kawata M., Kubo T.: Intervertebral disc regeneration using platelet-rich plasma and biodegradable gelatin hydrogel microspheres. Tissue Engineering 13(1):147-158.(2007)

Xue H-G., Yang C-Y., Yamamoto N., Ozawa H.: Fiber connections of the periventricular pretectal nucleus in a teleost, tilapia (Oreochromis niloticus). Neuroscience Research 57(2):184-193.(2007)

2006

Xue H-G., Yang C-Y., Ito H., Yamamoto N., Ozawa H.: Primary and secondary sensory trigeminal projections in a cyprinid teleost, carp (Cyprinus carpio). The Journal of Comparative Neurology 499(4):626-644. (2006)

Kinoshita M., Ito E., Urano A., Ito H., Yamamoto N.: Periventricular efferent neurons in the optic tectum of rainbow trout. The Journal of Comparative Neurology 499(4):546-564. (2006)

Kokawa T., Saigusa H., Aino I., Matsuoka C., Nakamura T., Tanuma K., Yamashita K., Niimi S.: Physiological studies of retrieve movement of the human tongue. Journal of Voice 20(3):414-422. (2006)

Xue H-G., Yamamoto N., Yang C-Y., Kerem G., Yoshimoto M., Sawai N., Ito H., Ozawa H.: Projections of the sensory trigeminal nucleus in a percomorph teleost, Tilapia (Orepchromis niloticus). The Journal of Comparative Neurology 495(3):279-298. (2006)

Saigusa H., Tanuma K., Yamasita K., Saigusa M., Niimi S.: Nerve fiber analysis for the lingual nerve of the human adult subjects. Surgical and Radiologic Anatomy 28(1):59-65. (2006))

2005

Tanaka M., Iijima N., Miyamoto Y., Fukusumi S., Itoh Y., Ibata Y., Ozawa H.: Neurons expressing relaxin 3/INSL7 in the nucleus incertus respond to stress. European Journal of Neuroscience 21(6):1659-1670. (2005)

Han F., Ozawa H., Matsuda K., Nishi M., Kawata M.: Colocalization of mineralocorticoid receptor and glucocorticoid receptor in the hippocampus and hypothalamus. Neuroscience Research 51(4):371-381.(2005)

Xue H-G., Yang C-Y., Ishida S., Ishizaka K., Ishihara A., Ishida A., Tanuma K.: Duplicate testicular veins accompanied by anomalies of the testicular arteries. Annals of Anatomy 187(4):393-398.(2005)

Yamamoto N., Ito H.: Fiber connections of the central nucleus of semicircular torus in cyprinids. The Journal of Comparative Neurology 491(3): 186-211. (2005)

Yamamoto N., Ito H.: Fiber connections of the anterior preglomerular nucleus in cyprinids with notes on telencephalic connections of the preglomerular complex. The Journal of Comparative Neurology 491(3):212-233. (2005)

Kawate T., Sakamoto H., Yang C-Y., Li Y., Shimada O., Astumi S.: Immunohistochemical study of delta and mu opioid receptors on synaptic glomeruli with substance P-positive central terminals in chicken dorsal horn. Neuroscience Research 53(3):279-287. (2005)

Sano K., Hyakusoku H., Tanuma K.: Clinical reappraisal of the segmental pectoralis major turn-over flap for coverrage of the local mediastinal wound. Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery 39(5):290-294. (2005)

Xue H-G., Yang C-Y., Yamamoto N., Ito H., Ozawa H.: An indirect trigeminocerebellar pathway through the nucleus lateralis valvulae in a perciform teleost, Oreochromis niloticus. Neuroscience Letters 390(2): 104-108. (2005)